Insulators and imprinting from flies to mammals
<p>Abstract</p> <p>The nuclear factor CTCF has been shown to be necessary for the maintenance of genetic imprinting at the mammalian H19/Igf2 locus. MacDonald and colleagues now report in <it>BMC Biology </it>that the mechanisms responsible for maintaining the imprinted...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2010-07-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/8/104 |
| Summary: | <p>Abstract</p> <p>The nuclear factor CTCF has been shown to be necessary for the maintenance of genetic imprinting at the mammalian H19/Igf2 locus. MacDonald and colleagues now report in <it>BMC Biology </it>that the mechanisms responsible for maintaining the imprinted state in <it>Drosophila </it>may be evolutionarily conserved and that CTCF may also play a critical role in this process.</p> <p>See research article <url>http://www.biomedcentral.com/1741-7007/8/105</url></p> |
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| ISSN: | 1741-7007 |