On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry Data
In the last decade, matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS), also called as MALDI-imaging, has proven its potential in proteomics and was successfully applied to various types of biomedical problems, in particular to histopathological label-free analysis o...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2012-03-01
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| Series: | Journal of Integrative Bioinformatics |
| Online Access: | http://www.degruyter.com/view/j/jib.2012.9.issue-1/biecoll-jib-2012-189/biecoll-jib-2012-189.xml?format=INT |
| _version_ | 1811324461289308160 |
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| author | Trede Dennis Kobarg Jan Hendrik Oetjen Janina Thiele Herbert Maass Peter Alexandrov Theodore |
| author_facet | Trede Dennis Kobarg Jan Hendrik Oetjen Janina Thiele Herbert Maass Peter Alexandrov Theodore |
| author_sort | Trede Dennis |
| collection | DOAJ |
| description | In the last decade, matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS), also called as MALDI-imaging, has proven its potential in proteomics and was successfully applied to various types of biomedical problems, in particular to histopathological label-free analysis of tissue sections. In histopathology, MALDI-imaging is used as a general analytic tool revealing the functional proteomic structure of tissue sections, and as a discovery tool for detecting new biomarkers discriminating a region annotated by an experienced histologist, in particular, for cancer studies. |
| first_indexed | 2024-04-13T14:14:44Z |
| format | Article |
| id | doaj.art-de8ea239b8c547468dcf7273ddd7c978 |
| institution | Directory Open Access Journal |
| issn | 1613-4516 |
| language | English |
| last_indexed | 2024-04-13T14:14:44Z |
| publishDate | 2012-03-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Journal of Integrative Bioinformatics |
| spelling | doaj.art-de8ea239b8c547468dcf7273ddd7c9782022-12-22T02:43:41ZengDe GruyterJournal of Integrative Bioinformatics1613-45162012-03-019111110.1515/jib-2012-189biecoll-jib-2012-189On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry DataTrede Dennis0Kobarg Jan Hendrik1Oetjen Janina2Thiele Herbert3Maass Peter4Alexandrov Theodore5Steinbeis Innovation Center SCiLS (Scientific Computing in Life Sciences), Richard-Dehmel-Str. 69, 28211 Bremen, http://www.scils.de GermanyZentrum für Technomathematik, Universität Bremen, Bibliothekstr. 1, 28359 Bremen, http://www.zetem.uni-bremen.de, GermanyZentrum für Technomathematik, Universität Bremen, Bibliothekstr. 1, 28359 Bremen, http://www.zetem.uni-bremen.de GermanyBruker Daltonik GmbH, Fahrenheitstr. 4, 28359 Bremen, http://www.bdal.de, GermanySteinbeis Innovation Center SCiLS (Scientific Computing in Life Sciences), Richard-Dehmel-Str. 69, 28211 Bremen, http://www.scils.de GermanySteinbeis Innovation Center SCiLS (Scientific Computing in Life Sciences), Richard-Dehmel-Str. 69, 28211 Bremen, http://www.scils.de United States of AmericaIn the last decade, matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS), also called as MALDI-imaging, has proven its potential in proteomics and was successfully applied to various types of biomedical problems, in particular to histopathological label-free analysis of tissue sections. In histopathology, MALDI-imaging is used as a general analytic tool revealing the functional proteomic structure of tissue sections, and as a discovery tool for detecting new biomarkers discriminating a region annotated by an experienced histologist, in particular, for cancer studies.http://www.degruyter.com/view/j/jib.2012.9.issue-1/biecoll-jib-2012-189/biecoll-jib-2012-189.xml?format=INT |
| spellingShingle | Trede Dennis Kobarg Jan Hendrik Oetjen Janina Thiele Herbert Maass Peter Alexandrov Theodore On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry Data Journal of Integrative Bioinformatics |
| title | On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry Data |
| title_full | On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry Data |
| title_fullStr | On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry Data |
| title_full_unstemmed | On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry Data |
| title_short | On the Importance of Mathematical Methods for Analysis of MALDI-Imaging Mass Spectrometry Data |
| title_sort | on the importance of mathematical methods for analysis of maldi imaging mass spectrometry data |
| url | http://www.degruyter.com/view/j/jib.2012.9.issue-1/biecoll-jib-2012-189/biecoll-jib-2012-189.xml?format=INT |
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