Primary Head and Neck Tumour-Derived Fibroblasts Promote Lymphangiogenesis in a Lymphatic Organotypic Co-culture Model

Primary Head and Neck Tumour-Derived Fibroblasts Promote Lymphangiogenesis in a Lymphatic Organotypic Co-culture Model

Background: In head and neck cancer, intratumour lymphatic density and tumour lymphangiogenesis have been correlated with lymphatic metastasis, making lymphangiogenesis a promising therapeutic target. However, inter-patient tumour heterogeneity makes it challenging to predict tumour progression and...

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Bibliographic Details
Main Authors: Karina M. Lugo-Cintrón, José M. Ayuso, Mouhita Humayun, Max M. Gong, Sheena C. Kerr, Suzanne M. Ponik, Paul M. Harari, María Virumbrales-Muñoz, David J. Beebe
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:EBioMedicine
Subjects:
Microfluidics
Fibroblasts
Patient-Specific Model
Lymphatics
lymphangiogenesis
Head and Neck Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421004278

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http://www.sciencedirect.com/science/article/pii/S2352396421004278

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