Alternative starting regimen with aripiprazole long-acting treatments, a case report
Introduction Aripiprazole long-acting treatments can significantly control symptom, improve adherence and reduce the risk of relapse compared to oral drugs. An alternative start-up guideline has recently been approved in several countries that simplifies its administration. Objectives To present a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933822018661/type/journal_article |
| _version_ | 1797617241486786560 |
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| author | M. Huete Naval B. Serván M.E. Expósito Durán P. Albarracin E. Herrero Pellón R. Galerón |
| author_facet | M. Huete Naval B. Serván M.E. Expósito Durán P. Albarracin E. Herrero Pellón R. Galerón |
| author_sort | M. Huete Naval |
| collection | DOAJ |
| description |
Introduction
Aripiprazole long-acting treatments can significantly control symptom, improve adherence and reduce the risk of relapse compared to oral drugs. An alternative start-up guideline has recently been approved in several countries that simplifies its administration.
Objectives
To present a case report of a patient with schizophrenia treated with alternative starting regimen of aripiprazole long-acting treatment.
Methods
Presentation of a clinical case supported by a non-systematic review of literature.
Results
We present the case of a 22-year-old patient diagnosed with schizophrenia, whose symptoms started after the birth of her son, 2 years ago. She has presented a poor clinical evolution, requiring several admissions to our inpatient service after discontinuation of her medication. The patient has taken different antipsychotics, including olanzapine and paliperidone long-acting treatment, which were suspended due to side effects (weight gain and increased prolactin levels). A switch to oral aripiprazole 20mg was made, which showed good response and tolerance. Given the persistence of irregular intake, it was decided to switch to aripiprazole long-acting treatment, applying an alternative initial regime consisting of two doses of aripiprazole long-acting treatments 400mg and one oral aripiprazole 20mg. The patient has since had no delusions or hallucinations and is living independently at home.
Conclusions
The administration of a simplified initial regime with aripiprazole long-acting treatments could improve therapeutic adherence while maintaining the same effectiveness and similar side effects.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:53:00Z |
| format | Article |
| id | doaj.art-de8ee189479c49fb87c4d193b11605db |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:53:00Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-de8ee189479c49fb87c4d193b11605db2023-11-17T05:06:30ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S723S72310.1192/j.eurpsy.2022.1866Alternative starting regimen with aripiprazole long-acting treatments, a case reportM. Huete Naval0B. Serván1M.E. Expósito Durán2P. Albarracin3E. Herrero Pellón4R. Galerón5Hospital Clínico San Carlos, Institute Of Psychiatry And Mental Health, Madrid, SpainHospital Universitario Clínico San Carlos, Psychiatry And Mental Health, Madrid, SpainHospital Clínico San Carlos, Instituto De Psiquiatría Y Salud Mental, Madrid, SpainHospital Universitario Clínico San Carlos, Psychiatry And Mental Health, Madrid, SpainHospital Clínico San Carlos, Institute Of Psychiatry And Mental Health, Madrid, SpainHospital Clínico San Carlos, Institute Of Psychiatry And Mental Health, Madrid, Spain Introduction Aripiprazole long-acting treatments can significantly control symptom, improve adherence and reduce the risk of relapse compared to oral drugs. An alternative start-up guideline has recently been approved in several countries that simplifies its administration. Objectives To present a case report of a patient with schizophrenia treated with alternative starting regimen of aripiprazole long-acting treatment. Methods Presentation of a clinical case supported by a non-systematic review of literature. Results We present the case of a 22-year-old patient diagnosed with schizophrenia, whose symptoms started after the birth of her son, 2 years ago. She has presented a poor clinical evolution, requiring several admissions to our inpatient service after discontinuation of her medication. The patient has taken different antipsychotics, including olanzapine and paliperidone long-acting treatment, which were suspended due to side effects (weight gain and increased prolactin levels). A switch to oral aripiprazole 20mg was made, which showed good response and tolerance. Given the persistence of irregular intake, it was decided to switch to aripiprazole long-acting treatment, applying an alternative initial regime consisting of two doses of aripiprazole long-acting treatments 400mg and one oral aripiprazole 20mg. The patient has since had no delusions or hallucinations and is living independently at home. Conclusions The administration of a simplified initial regime with aripiprazole long-acting treatments could improve therapeutic adherence while maintaining the same effectiveness and similar side effects. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822018661/type/journal_articleAripiprazolelong-acting treatments |
| spellingShingle | M. Huete Naval B. Serván M.E. Expósito Durán P. Albarracin E. Herrero Pellón R. Galerón Alternative starting regimen with aripiprazole long-acting treatments, a case report European Psychiatry Aripiprazole long-acting treatments |
| title | Alternative starting regimen with aripiprazole long-acting treatments, a case report |
| title_full | Alternative starting regimen with aripiprazole long-acting treatments, a case report |
| title_fullStr | Alternative starting regimen with aripiprazole long-acting treatments, a case report |
| title_full_unstemmed | Alternative starting regimen with aripiprazole long-acting treatments, a case report |
| title_short | Alternative starting regimen with aripiprazole long-acting treatments, a case report |
| title_sort | alternative starting regimen with aripiprazole long acting treatments a case report |
| topic | Aripiprazole long-acting treatments |
| url | https://www.cambridge.org/core/product/identifier/S0924933822018661/type/journal_article |
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