Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-up
Although coronavirus disease 2019 (COVID-19) primarily affects the respiratory system, this disease can affect multiple systems, including the musculoskeletal system. However, studies regarding the effect of COVID-19 on musculoskeletal system are limited. This study analyzed the bone mineral density...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Editorial Office of Computerized Tomography Theory and Application
2023-05-01
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| Series: | CT Lilun yu yingyong yanjiu |
| Subjects: | |
| Online Access: | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2023.052 |
| _version_ | 1797810318606336000 |
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| author | Wenmin GUAN Xuan WEI Jing SUN Wei WEI Tingting ZHANG Ying YAN Lijun SONG Husheng QIAN Daning WANG Guanghong LIU Meiqin QIAO Lu REN Zhenghan YANG Yan XU Zhenchang WANG |
| author_facet | Wenmin GUAN Xuan WEI Jing SUN Wei WEI Tingting ZHANG Ying YAN Lijun SONG Husheng QIAN Daning WANG Guanghong LIU Meiqin QIAO Lu REN Zhenghan YANG Yan XU Zhenchang WANG |
| author_sort | Wenmin GUAN |
| collection | DOAJ |
| description | Although coronavirus disease 2019 (COVID-19) primarily affects the respiratory system, this disease can affect multiple systems, including the musculoskeletal system. However, studies regarding the effect of COVID-19 on musculoskeletal system are limited. This study analyzed the bone mineral density (BMD) and body composition of 33 patients with COVID-19 using their chest CT scans at admission, discharge, and one-year follow-up. Among the patients, 2 were asymptomatic, 8 had mild symptoms, 19 had ordinary symptoms, and 4 had severe symptoms, and no critical patients were included. The mean length of hospital stay was (29.5±9.6) days, and the mean duration to follow-up was (423.0±53.6) days. The study found no significant changes in BMD of segmental or total thoracic vertebrae at admission, discharge, and one-year follow-up. No significant changes were observed in the subcutaneous adipose tissue (SAT) area, visceral adipose tissue (VAT) area, and total adipose tissue (TAT) of the mid-slice of the T12~L1 intervertebral disc. However, the asymptomatic and mild group had a higher average BMD of the T1~T12 than that of the common and severe group at admission and one-year follow-up. The common and severe group had higher VAT and TAT area than those of the asymptomatic and mild group at admission and one-year follow-up. This study provides valuable insights into the effects of COVID-19 on the musculoskeletal system and suggests that COVID-19 does not significantly affect thoracic BMD and abdominal adipose tissue after one year of infection. |
| first_indexed | 2024-03-13T07:06:58Z |
| format | Article |
| id | doaj.art-de93ccf079724b7ea3a0d869f6d455cf |
| institution | Directory Open Access Journal |
| issn | 1004-4140 |
| language | English |
| last_indexed | 2024-03-13T07:06:58Z |
| publishDate | 2023-05-01 |
| publisher | Editorial Office of Computerized Tomography Theory and Application |
| record_format | Article |
| series | CT Lilun yu yingyong yanjiu |
| spelling | doaj.art-de93ccf079724b7ea3a0d869f6d455cf2023-06-06T09:49:37ZengEditorial Office of Computerized Tomography Theory and ApplicationCT Lilun yu yingyong yanjiu1004-41402023-05-0132341141810.15953/j.ctta.2023.0522023.052Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-upWenmin GUANXuan WEIJing SUNWei WEITingting ZHANGYing YANLijun SONGHusheng QIANDaning WANG0Guanghong LIU1Meiqin QIAO2Lu REN3Zhenghan YANGYan XUZhenchang WANGDepartment of Radiology, Yanbian Korean Medical Hospital, Yanji 133000, ChinaImage Center, Baicheng Municipal Hospital, Baicheng 137000, ChinaDepartment of Radiology, The Third Affiliated Hospital of Luohe Medical College, Luohe 462000, ChinaMedical Imaging Department, Ordos Central Hospital, Ordos 017000, ChinaAlthough coronavirus disease 2019 (COVID-19) primarily affects the respiratory system, this disease can affect multiple systems, including the musculoskeletal system. However, studies regarding the effect of COVID-19 on musculoskeletal system are limited. This study analyzed the bone mineral density (BMD) and body composition of 33 patients with COVID-19 using their chest CT scans at admission, discharge, and one-year follow-up. Among the patients, 2 were asymptomatic, 8 had mild symptoms, 19 had ordinary symptoms, and 4 had severe symptoms, and no critical patients were included. The mean length of hospital stay was (29.5±9.6) days, and the mean duration to follow-up was (423.0±53.6) days. The study found no significant changes in BMD of segmental or total thoracic vertebrae at admission, discharge, and one-year follow-up. No significant changes were observed in the subcutaneous adipose tissue (SAT) area, visceral adipose tissue (VAT) area, and total adipose tissue (TAT) of the mid-slice of the T12~L1 intervertebral disc. However, the asymptomatic and mild group had a higher average BMD of the T1~T12 than that of the common and severe group at admission and one-year follow-up. The common and severe group had higher VAT and TAT area than those of the asymptomatic and mild group at admission and one-year follow-up. This study provides valuable insights into the effects of COVID-19 on the musculoskeletal system and suggests that COVID-19 does not significantly affect thoracic BMD and abdominal adipose tissue after one year of infection.https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2023.052quantitative ctmultimodal imagecoronavirus disease 2019bone mineral densitybody composition |
| spellingShingle | Wenmin GUAN Xuan WEI Jing SUN Wei WEI Tingting ZHANG Ying YAN Lijun SONG Husheng QIAN Daning WANG Guanghong LIU Meiqin QIAO Lu REN Zhenghan YANG Yan XU Zhenchang WANG Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-up CT Lilun yu yingyong yanjiu quantitative ct multimodal image coronavirus disease 2019 bone mineral density body composition |
| title | Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-up |
| title_full | Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-up |
| title_fullStr | Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-up |
| title_full_unstemmed | Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-up |
| title_short | Bone Mineral Density and Body Composition Characteristics of Patients with Coronavirus Disease 2019 after One-year Follow-up |
| title_sort | bone mineral density and body composition characteristics of patients with coronavirus disease 2019 after one year follow up |
| topic | quantitative ct multimodal image coronavirus disease 2019 bone mineral density body composition |
| url | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2023.052 |
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