1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) Rapidly Resolves LPS-Induced Acute Lung Injury Through the Effective Control of Neutrophil Recruitment

1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) Rapidly Resolves LPS-Induced Acute Lung Injury Through the Effective Control of Neutrophil Recruitment

Acute lung injury (ALI) is an acute respiratory failure that is associated with excessive neutrophil recruitment and high mortality. To assess the efficacy of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) as a therapeutic agent for ALI, this compound was administered orally to mice challenged...

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Bibliographic Details
Main Authors: Ha-Reum Lee, Su-Hyun Shin, Joo Heon Kim, Ki-Young Sohn, Sun Young Yoon, Jae Wha Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
acute lung injury
neutrophil
transmigration
inflammation
PLAG
resolution
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02177/full

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