Cholestatic hepatitis due to Salmonella typhi

Salmonella infection occurs worldwide and is still an important public health problem in many developing countries. The infection can affect almost all major organs including the liver. Severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. In this paper, a 39-...

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Main Authors: Ayse Albayrak, Sibel Seda Gunbey, Ferda Aktas
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:Clinics and Practice
Subjects:
Online Access:https://www.clinicsandpractice.org/index.php/cp/article/view/9
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author Ayse Albayrak
Sibel Seda Gunbey
Ferda Aktas
author_facet Ayse Albayrak
Sibel Seda Gunbey
Ferda Aktas
author_sort Ayse Albayrak
collection DOAJ
description Salmonella infection occurs worldwide and is still an important public health problem in many developing countries. The infection can affect almost all major organs including the liver. Severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. In this paper, a 39-year-old male with acute cholestatic typhoid hepatitis is presented. The case had a tender hepatomegaly and elevated serum alanine and aspartate transaminase, alkaline phosphatase, and gamma glutamyl transferase levels; these features cannot been distinguished from those of acute viral hepatitis. Serological and viral markers of acute viral hepatitis were negative. No pathology could be determined in abdomen Ultrasonography (USG) or Magnetic Reso - nance (MR) Cholangiography. As enteric fever is a common infection, the recognition of salmonella hepatitis is of clinical importance. When patients from an endemic or outbreak area present acute febrile hepatitis, typhoid fever should be a consideration.
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spelling doaj.art-de95ffe8f64c4b7abe4636a649e7ed9d2022-12-22T02:12:17ZengMDPI AGClinics and Practice2039-72752039-72832011-04-011110.4081/cp.2011.e1313Cholestatic hepatitis due to Salmonella typhiAyse Albayrak0Sibel Seda Gunbey1Ferda Aktas2Department of Infectious Diseases and Clinical Microbiology, Erzurum Region Education and Research Hospital, Erzurum, Turkey.Department of Infectious Diseases and Clinical Microbiology, Erzurum Region Education and Research Hospital, Erzurum, Turkey.Department of Clinical Microbiology, Erzurum Region Education and Research Hospital, TurkeySalmonella infection occurs worldwide and is still an important public health problem in many developing countries. The infection can affect almost all major organs including the liver. Severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. In this paper, a 39-year-old male with acute cholestatic typhoid hepatitis is presented. The case had a tender hepatomegaly and elevated serum alanine and aspartate transaminase, alkaline phosphatase, and gamma glutamyl transferase levels; these features cannot been distinguished from those of acute viral hepatitis. Serological and viral markers of acute viral hepatitis were negative. No pathology could be determined in abdomen Ultrasonography (USG) or Magnetic Reso - nance (MR) Cholangiography. As enteric fever is a common infection, the recognition of salmonella hepatitis is of clinical importance. When patients from an endemic or outbreak area present acute febrile hepatitis, typhoid fever should be a consideration.https://www.clinicsandpractice.org/index.php/cp/article/view/9typhoid feveracute hepatitisSalmonella typhiceftriaxone.
spellingShingle Ayse Albayrak
Sibel Seda Gunbey
Ferda Aktas
Cholestatic hepatitis due to Salmonella typhi
Clinics and Practice
typhoid fever
acute hepatitis
Salmonella typhi
ceftriaxone.
title Cholestatic hepatitis due to Salmonella typhi
title_full Cholestatic hepatitis due to Salmonella typhi
title_fullStr Cholestatic hepatitis due to Salmonella typhi
title_full_unstemmed Cholestatic hepatitis due to Salmonella typhi
title_short Cholestatic hepatitis due to Salmonella typhi
title_sort cholestatic hepatitis due to salmonella typhi
topic typhoid fever
acute hepatitis
Salmonella typhi
ceftriaxone.
url https://www.clinicsandpractice.org/index.php/cp/article/view/9
work_keys_str_mv AT aysealbayrak cholestatichepatitisduetosalmonellatyphi
AT sibelsedagunbey cholestatichepatitisduetosalmonellatyphi
AT ferdaaktas cholestatichepatitisduetosalmonellatyphi