Cholestatic hepatitis due to Salmonella typhi
Salmonella infection occurs worldwide and is still an important public health problem in many developing countries. The infection can affect almost all major organs including the liver. Severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. In this paper, a 39-...
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Format: | Article |
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MDPI AG
2011-04-01
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Series: | Clinics and Practice |
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Online Access: | https://www.clinicsandpractice.org/index.php/cp/article/view/9 |
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author | Ayse Albayrak Sibel Seda Gunbey Ferda Aktas |
author_facet | Ayse Albayrak Sibel Seda Gunbey Ferda Aktas |
author_sort | Ayse Albayrak |
collection | DOAJ |
description | Salmonella infection occurs worldwide and is still an important public health problem in many developing countries. The infection can affect almost all major organs including the liver. Severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. In this paper, a 39-year-old male with acute cholestatic typhoid hepatitis is presented. The case had a tender hepatomegaly and elevated serum alanine and aspartate transaminase, alkaline phosphatase, and gamma glutamyl transferase levels; these features cannot been distinguished from those of acute viral hepatitis. Serological and viral markers of acute viral hepatitis were negative. No pathology could be determined in abdomen Ultrasonography (USG) or Magnetic Reso - nance (MR) Cholangiography. As enteric fever is a common infection, the recognition of salmonella hepatitis is of clinical importance. When patients from an endemic or outbreak area present acute febrile hepatitis, typhoid fever should be a consideration. |
first_indexed | 2024-04-14T04:26:46Z |
format | Article |
id | doaj.art-de95ffe8f64c4b7abe4636a649e7ed9d |
institution | Directory Open Access Journal |
issn | 2039-7275 2039-7283 |
language | English |
last_indexed | 2024-04-14T04:26:46Z |
publishDate | 2011-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Clinics and Practice |
spelling | doaj.art-de95ffe8f64c4b7abe4636a649e7ed9d2022-12-22T02:12:17ZengMDPI AGClinics and Practice2039-72752039-72832011-04-011110.4081/cp.2011.e1313Cholestatic hepatitis due to Salmonella typhiAyse Albayrak0Sibel Seda Gunbey1Ferda Aktas2Department of Infectious Diseases and Clinical Microbiology, Erzurum Region Education and Research Hospital, Erzurum, Turkey.Department of Infectious Diseases and Clinical Microbiology, Erzurum Region Education and Research Hospital, Erzurum, Turkey.Department of Clinical Microbiology, Erzurum Region Education and Research Hospital, TurkeySalmonella infection occurs worldwide and is still an important public health problem in many developing countries. The infection can affect almost all major organs including the liver. Severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. In this paper, a 39-year-old male with acute cholestatic typhoid hepatitis is presented. The case had a tender hepatomegaly and elevated serum alanine and aspartate transaminase, alkaline phosphatase, and gamma glutamyl transferase levels; these features cannot been distinguished from those of acute viral hepatitis. Serological and viral markers of acute viral hepatitis were negative. No pathology could be determined in abdomen Ultrasonography (USG) or Magnetic Reso - nance (MR) Cholangiography. As enteric fever is a common infection, the recognition of salmonella hepatitis is of clinical importance. When patients from an endemic or outbreak area present acute febrile hepatitis, typhoid fever should be a consideration.https://www.clinicsandpractice.org/index.php/cp/article/view/9typhoid feveracute hepatitisSalmonella typhiceftriaxone. |
spellingShingle | Ayse Albayrak Sibel Seda Gunbey Ferda Aktas Cholestatic hepatitis due to Salmonella typhi Clinics and Practice typhoid fever acute hepatitis Salmonella typhi ceftriaxone. |
title | Cholestatic hepatitis due to Salmonella typhi |
title_full | Cholestatic hepatitis due to Salmonella typhi |
title_fullStr | Cholestatic hepatitis due to Salmonella typhi |
title_full_unstemmed | Cholestatic hepatitis due to Salmonella typhi |
title_short | Cholestatic hepatitis due to Salmonella typhi |
title_sort | cholestatic hepatitis due to salmonella typhi |
topic | typhoid fever acute hepatitis Salmonella typhi ceftriaxone. |
url | https://www.clinicsandpractice.org/index.php/cp/article/view/9 |
work_keys_str_mv | AT aysealbayrak cholestatichepatitisduetosalmonellatyphi AT sibelsedagunbey cholestatichepatitisduetosalmonellatyphi AT ferdaaktas cholestatichepatitisduetosalmonellatyphi |