Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant Activities
<i>Hypochaeris laevigata</i> var. <i>hipponensis</i> (Asteraceae) is an endemic plant from Algeria. In the current study, we analyzed for the first time its chemical composition, especially phenolic constituents of dichloromethane (DCM), ethyl acetate (EA), and n-butanol (BuO...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/9/4/514 |
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| author | Nabila Souilah Zain Ullah Hamdi Bendif Kamel Medjroubi Tahar Hazmoune Tarek Hamel Mehmet Öztürk Gema Nieto Salah Akkal |
| author_facet | Nabila Souilah Zain Ullah Hamdi Bendif Kamel Medjroubi Tahar Hazmoune Tarek Hamel Mehmet Öztürk Gema Nieto Salah Akkal |
| author_sort | Nabila Souilah |
| collection | DOAJ |
| description | <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> (Asteraceae) is an endemic plant from Algeria. In the current study, we analyzed for the first time its chemical composition, especially phenolic constituents of dichloromethane (DCM), ethyl acetate (EA), and n-butanol (BuOH) fractionsof the aerial parts of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> by liquid chromatography-mass spectrometry (LC-MS/MS). The number of phenolic compounds detected in DCM, EA, and BuOH fractions were found to be 9, 20, and 15, respectively. More specifically, 12 phenolic acids were detected. Among them, quinic acid, chlorogenic acid, and caffeic acid were the most abundant ones. Meanwhile, only seven flavonoids were detected. Among them, rutin, apigetrin, and isoquercitrin were the major ones. We also determined the total phenolic and flavonoid contents, and fraction EA showed the highest values, followed by BuOH, and DCM fractions. Furthermore, the antioxidant action was dictated by five methods and the tested plant fractions demonstrated a noteworthy antioxidant action. |
| first_indexed | 2024-03-10T20:26:34Z |
| format | Article |
| id | doaj.art-de96007451da4263a59b344baf6cbb2d |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-10T20:26:34Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-de96007451da4263a59b344baf6cbb2d2023-11-19T21:47:50ZengMDPI AGPlants2223-77472020-04-019451410.3390/plants9040514Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant ActivitiesNabila Souilah0Zain Ullah1Hamdi Bendif2Kamel Medjroubi3Tahar Hazmoune4Tarek Hamel5Mehmet Öztürk6Gema Nieto7Salah Akkal8Laboratory of Optimization of Agricultural Production in Sub-Humid Zones (LOPAZS), Faculty of Science, University of Skikda, Skikda 21000, AlgeriaDepartment of Chemistry, Faculty of Sciences, University of Muğla Sitki Koçman, Muğla 48000, TurkeyDepartment of Natural Sciences and Life, Faculty of Science, University of M’sila, M’sila 28000, AlgeriaLaboratory of Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analyzes Department of Chemistry, Faculty of Exact Sciences, University of Constantine 1, Constantine 25000, AlgeriaLaboratory of Optimization of Agricultural Production in Sub-Humid Zones (LOPAZS), Faculty of Science, University of Skikda, Skikda 21000, AlgeriaDepartment of Natural Sciences and Life, Faculty of Science, University of Badji Mokhtar, Annaba 23000, AlgeriaDepartment of Chemistry, Faculty of Sciences, University of Muğla Sitki Koçman, Muğla 48000, TurkeyDepartment of Food Technology, Food Science and Nutrition, Faculty of Veterinary Sciences, Regional Campus of International Excellence “Campus Mare Nostrum”, Espinardo, 30071 Murcia, SpainLaboratory of Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analyzes Department of Chemistry, Faculty of Exact Sciences, University of Constantine 1, Constantine 25000, Algeria<i>Hypochaeris laevigata</i> var. <i>hipponensis</i> (Asteraceae) is an endemic plant from Algeria. In the current study, we analyzed for the first time its chemical composition, especially phenolic constituents of dichloromethane (DCM), ethyl acetate (EA), and n-butanol (BuOH) fractionsof the aerial parts of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> by liquid chromatography-mass spectrometry (LC-MS/MS). The number of phenolic compounds detected in DCM, EA, and BuOH fractions were found to be 9, 20, and 15, respectively. More specifically, 12 phenolic acids were detected. Among them, quinic acid, chlorogenic acid, and caffeic acid were the most abundant ones. Meanwhile, only seven flavonoids were detected. Among them, rutin, apigetrin, and isoquercitrin were the major ones. We also determined the total phenolic and flavonoid contents, and fraction EA showed the highest values, followed by BuOH, and DCM fractions. Furthermore, the antioxidant action was dictated by five methods and the tested plant fractions demonstrated a noteworthy antioxidant action.https://www.mdpi.com/2223-7747/9/4/514<i>Hypochaeris laevigata</i> var. <i>hipponensis</i>Asteraceaephenolic compoundsantioxidants activitiesLC-MS/MS |
| spellingShingle | Nabila Souilah Zain Ullah Hamdi Bendif Kamel Medjroubi Tahar Hazmoune Tarek Hamel Mehmet Öztürk Gema Nieto Salah Akkal Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant Activities Plants <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> Asteraceae phenolic compounds antioxidants activities LC-MS/MS |
| title | Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant Activities |
| title_full | Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant Activities |
| title_fullStr | Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant Activities |
| title_full_unstemmed | Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant Activities |
| title_short | Phenolic Compounds from An Algerian Endemic Species of <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> and Investigation of Antioxidant Activities |
| title_sort | phenolic compounds from an algerian endemic species of i hypochaeris laevigata i var i hipponensis i and investigation of antioxidant activities |
| topic | <i>Hypochaeris laevigata</i> var. <i>hipponensis</i> Asteraceae phenolic compounds antioxidants activities LC-MS/MS |
| url | https://www.mdpi.com/2223-7747/9/4/514 |
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