S100A4 is elevated in axial spondyloarthritis: a potential link to disease severity

S100A4 is elevated in axial spondyloarthritis: a potential link to disease severity

Abstract Background S100A4 is a member of calcium binding S100 protein family well known for its role in cancer progression and metastasis. Nevertheless, S100A4 also serves as a negative regulator of bone formation. Dickkopf-1 (DKK-1), marker of bone remodelling, is also implicated in the process of...

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Main Authors: Barbora Šumová, Lucie Andrés Cerezo, Hana Hulejová, Klára Prajzlerová, Michal Tomčík, Kristýna Bubová, Jan Štěpán, Mária Filková, Tereza Kropáčková, Mariam Grigorian, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Rheumatology
Subjects:
S100A4
Axial spondyloarthritis
Disease severity
Disease duration
Syndesmophyte
Online Access:https://doi.org/10.1186/s41927-019-0110-7

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