Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria
BackgroundProteinuria is an important predictor of cardiovascular disease and mortality. Several studies reported the association between skipping breakfast and the prevalence of proteinuria. Furthermore, skipping breakfast was associated with an increased risk of obesity. Although proteinuria is hi...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.916374/full |
| _version_ | 1798042290597396480 |
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| author | Jun Muratsu Jun Muratsu Kei Kamide Kei Kamide Takashi Fujimoto Yasushi Takeya Yasushi Takeya Ken Sugimoto Yoshiaki Taniyama Atsuyuki Morishima Katsuhiko Sakaguchi Hiromi Rakugi |
| author_facet | Jun Muratsu Jun Muratsu Kei Kamide Kei Kamide Takashi Fujimoto Yasushi Takeya Yasushi Takeya Ken Sugimoto Yoshiaki Taniyama Atsuyuki Morishima Katsuhiko Sakaguchi Hiromi Rakugi |
| author_sort | Jun Muratsu |
| collection | DOAJ |
| description | BackgroundProteinuria is an important predictor of cardiovascular disease and mortality. Several studies reported the association between skipping breakfast and the prevalence of proteinuria. Furthermore, skipping breakfast was associated with an increased risk of obesity. Although proteinuria is highly prevalent in obese individuals, the association between the prevalence of proteinuria and low body mass index (BMI) was reported in a previous cross-sectional study in asymptomatic individuals without known kidney diseases. The aim of this cross-sectional study was to assess the clinical impact of BMI on the association between skipping breakfast and the prevalence of proteinuria in normal renal function subjects.MethodsThe present study included 26,888 subjects (15,875 males and 11,013 females) with an estimated glomerular filtration rate ≥60 ml/min/1.73 m2 and no history of kidney disease who underwent a health checkup in Sumitomo Hospital. The association between skipping breakfast and the prevalence of proteinuria (defined as dipstick proteinuria of ≥1+) was assessed using logistic regression models adjusted for clinically relevant factors.ResultsSkipping breakfast was reported in 3,306 males (20.8%) and 1,514 females (13.8%). Multivariable adjusted logistic regression models showed that skipping breakfast was significantly associated with the prevalence of proteinuria above 1+. This association was evident in lower BMI subjects, even after adjusting for clinically relevant factors (adjusted odds ratios of males and females were 1.67 [1.17–2.38] and 1.92 [1.31–2.82], respectively), whereas this association was not evident in higher BMI subjects.ConclusionLower BMI subjects with proteinuria might need to be careful about skipping breakfast. |
| first_indexed | 2024-04-11T22:33:25Z |
| format | Article |
| id | doaj.art-de9f7c12203b42099446a681f2e913bb |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-11T22:33:25Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-de9f7c12203b42099446a681f2e913bb2022-12-22T03:59:18ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-08-011310.3389/fendo.2022.916374916374Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuriaJun Muratsu0Jun Muratsu1Kei Kamide2Kei Kamide3Takashi Fujimoto4Yasushi Takeya5Yasushi Takeya6Ken Sugimoto7Yoshiaki Taniyama8Atsuyuki Morishima9Katsuhiko Sakaguchi10Hiromi Rakugi11Department of Nephrology and Hypertension, Sumitomo Hospital, Osaka, JapanDepartment of Nephrology, Rinku General Medical Center, Izumisano City, JapanDivision of Health Sciences, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of Nephrology and Hypertension, Sumitomo Hospital, Osaka, JapanDivision of Health Sciences, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of General and Geriatric Medicine, Kawasaki Medical School General Medical Center, Okayama, JapanDepartment of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of Nephrology and Hypertension, Sumitomo Hospital, Osaka, JapanDepartment of Nephrology and Hypertension, Sumitomo Hospital, Osaka, JapanDepartment of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, JapanBackgroundProteinuria is an important predictor of cardiovascular disease and mortality. Several studies reported the association between skipping breakfast and the prevalence of proteinuria. Furthermore, skipping breakfast was associated with an increased risk of obesity. Although proteinuria is highly prevalent in obese individuals, the association between the prevalence of proteinuria and low body mass index (BMI) was reported in a previous cross-sectional study in asymptomatic individuals without known kidney diseases. The aim of this cross-sectional study was to assess the clinical impact of BMI on the association between skipping breakfast and the prevalence of proteinuria in normal renal function subjects.MethodsThe present study included 26,888 subjects (15,875 males and 11,013 females) with an estimated glomerular filtration rate ≥60 ml/min/1.73 m2 and no history of kidney disease who underwent a health checkup in Sumitomo Hospital. The association between skipping breakfast and the prevalence of proteinuria (defined as dipstick proteinuria of ≥1+) was assessed using logistic regression models adjusted for clinically relevant factors.ResultsSkipping breakfast was reported in 3,306 males (20.8%) and 1,514 females (13.8%). Multivariable adjusted logistic regression models showed that skipping breakfast was significantly associated with the prevalence of proteinuria above 1+. This association was evident in lower BMI subjects, even after adjusting for clinically relevant factors (adjusted odds ratios of males and females were 1.67 [1.17–2.38] and 1.92 [1.31–2.82], respectively), whereas this association was not evident in higher BMI subjects.ConclusionLower BMI subjects with proteinuria might need to be careful about skipping breakfast.https://www.frontiersin.org/articles/10.3389/fendo.2022.916374/fullskipping breakfastproteinuriabody mass indexhealth checkupwaist circumference |
| spellingShingle | Jun Muratsu Jun Muratsu Kei Kamide Kei Kamide Takashi Fujimoto Yasushi Takeya Yasushi Takeya Ken Sugimoto Yoshiaki Taniyama Atsuyuki Morishima Katsuhiko Sakaguchi Hiromi Rakugi Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria Frontiers in Endocrinology skipping breakfast proteinuria body mass index health checkup waist circumference |
| title | Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria |
| title_full | Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria |
| title_fullStr | Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria |
| title_full_unstemmed | Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria |
| title_short | Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria |
| title_sort | lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria |
| topic | skipping breakfast proteinuria body mass index health checkup waist circumference |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.916374/full |
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