Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)

Background: Women's menstrual suppression is desired for many reasons. Menstrual suppresion, especially during the holidays, trips, camps, military exercises, special events, academic examinations or athletic events is desirable. This study, with emphasis on safety of megestrol acetate tablets,...

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Main Authors: Tajossadat Allameh, Zahra Allameh, Fatemeh Moatamedy
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2013-07-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/2846
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author Tajossadat Allameh
Zahra Allameh
Fatemeh Moatamedy
author_facet Tajossadat Allameh
Zahra Allameh
Fatemeh Moatamedy
author_sort Tajossadat Allameh
collection DOAJ
description Background: Women's menstrual suppression is desired for many reasons. Menstrual suppresion, especially during the holidays, trips, camps, military exercises, special events, academic examinations or athletic events is desirable. This study, with emphasis on safety of megestrol acetate tablets, aimed to determine the effect of this tablet on retardation of menstruation compared with low-dose estrogen combined oral contraceptives (LD). Methods: In this clinical-trial study, 140 applicants to postpone menstruation left for pilgrimage randomly devided to two groups, LD and megestrol acetate recipients. Data were collected through a researcher-made questionnaire and were analyzed by Mann-Whitney Uand chi-square tests. Findings: The frequency of individuals reported symptoms such as headache or dizziness (P < 0.05), nausea or vomiting (P < 0.05), changes in appetite (P < 0.05) and changes in sexual desire (P < 0.05), was significantly more in the LD recipients compared with megestrol acetates. Conclusion: Megestrol acetate can be seen as a drug with the same efficacy of LD, but safer than it, to postpone the menstruation.
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spelling doaj.art-de9fed03bb8548969de841d08dec5ee52023-08-02T07:48:45ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2013-07-01312345325431325Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)Tajossadat Allameh0Zahra Allameh1Fatemeh Moatamedy2Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranStudent of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, IranBackground: Women's menstrual suppression is desired for many reasons. Menstrual suppresion, especially during the holidays, trips, camps, military exercises, special events, academic examinations or athletic events is desirable. This study, with emphasis on safety of megestrol acetate tablets, aimed to determine the effect of this tablet on retardation of menstruation compared with low-dose estrogen combined oral contraceptives (LD). Methods: In this clinical-trial study, 140 applicants to postpone menstruation left for pilgrimage randomly devided to two groups, LD and megestrol acetate recipients. Data were collected through a researcher-made questionnaire and were analyzed by Mann-Whitney Uand chi-square tests. Findings: The frequency of individuals reported symptoms such as headache or dizziness (P < 0.05), nausea or vomiting (P < 0.05), changes in appetite (P < 0.05) and changes in sexual desire (P < 0.05), was significantly more in the LD recipients compared with megestrol acetates. Conclusion: Megestrol acetate can be seen as a drug with the same efficacy of LD, but safer than it, to postpone the menstruation.http://jims.mui.ac.ir/index.php/jims/article/view/2846Postpone menstruationLow-dose estrogen combined oral contraceptives (LD)Megestrol acetate
spellingShingle Tajossadat Allameh
Zahra Allameh
Fatemeh Moatamedy
Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)
مجله دانشکده پزشکی اصفهان
Postpone menstruation
Low-dose estrogen combined oral contraceptives (LD)
Megestrol acetate
title Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)
title_full Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)
title_fullStr Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)
title_full_unstemmed Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)
title_short Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared with Low-Dose Estrogen Combined Oral Contraceptives (LD)
title_sort efficacy and side effects of megestrol acetate tablets on postpone menstruation compared with low dose estrogen combined oral contraceptives ld
topic Postpone menstruation
Low-dose estrogen combined oral contraceptives (LD)
Megestrol acetate
url http://jims.mui.ac.ir/index.php/jims/article/view/2846
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