Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome
Kinesins are essential motor molecules of the microtubule cytoskeleton. All eukaryotic organisms have several genes encoding kinesin proteins, which are necessary for various cell biological functions. During the vegetative growth of filamentous basidiomycetes, the apical cells of long leading hypha...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/8/3/294 |
| _version_ | 1797446524281552896 |
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| author | Marjatta Raudaskoski |
| author_facet | Marjatta Raudaskoski |
| author_sort | Marjatta Raudaskoski |
| collection | DOAJ |
| description | Kinesins are essential motor molecules of the microtubule cytoskeleton. All eukaryotic organisms have several genes encoding kinesin proteins, which are necessary for various cell biological functions. During the vegetative growth of filamentous basidiomycetes, the apical cells of long leading hyphae have microtubules extending toward the tip. The reciprocal exchange and migration of nuclei between haploid hyphae at mating is also dependent on cytoskeletal structures, including the microtubules and their motor molecules. In dikaryotic hyphae, resulting from a compatible mating, the nuclear location, synchronous nuclear division, and extensive nuclear separation at telophase are microtubule-dependent processes that involve unidentified molecular motors. The genome of <i>Schizophyllum commune</i> is analyzed as an example of a species belonging to the Basidiomycota subclass, Agaricomycetes. In this subclass, the investigation of cell biology is restricted to a few species. Instead, the whole genome sequences of several species are now available. The analyses of the mating type genes and the genes necessary for fruiting body formation or wood degrading enzymes in several genomes of Agaricomycetes have shown that they are controlled by comparable systems. This supports the idea that the genes regulating the cell biological process in a model fungus, such as the genes encoding kinesin motor molecules, are also functional in other filamentous Agaricomycetes. |
| first_indexed | 2024-03-09T13:42:44Z |
| format | Article |
| id | doaj.art-dea49c17258c4b4ebee186b9f241ffdb |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-09T13:42:44Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-dea49c17258c4b4ebee186b9f241ffdb2023-11-30T21:05:27ZengMDPI AGJournal of Fungi2309-608X2022-03-018329410.3390/jof8030294Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> GenomeMarjatta Raudaskoski0Molecular Plant Biology, Department of Life Technologies, University of Turku, 20014 Turku, FinlandKinesins are essential motor molecules of the microtubule cytoskeleton. All eukaryotic organisms have several genes encoding kinesin proteins, which are necessary for various cell biological functions. During the vegetative growth of filamentous basidiomycetes, the apical cells of long leading hyphae have microtubules extending toward the tip. The reciprocal exchange and migration of nuclei between haploid hyphae at mating is also dependent on cytoskeletal structures, including the microtubules and their motor molecules. In dikaryotic hyphae, resulting from a compatible mating, the nuclear location, synchronous nuclear division, and extensive nuclear separation at telophase are microtubule-dependent processes that involve unidentified molecular motors. The genome of <i>Schizophyllum commune</i> is analyzed as an example of a species belonging to the Basidiomycota subclass, Agaricomycetes. In this subclass, the investigation of cell biology is restricted to a few species. Instead, the whole genome sequences of several species are now available. The analyses of the mating type genes and the genes necessary for fruiting body formation or wood degrading enzymes in several genomes of Agaricomycetes have shown that they are controlled by comparable systems. This supports the idea that the genes regulating the cell biological process in a model fungus, such as the genes encoding kinesin motor molecules, are also functional in other filamentous Agaricomycetes.https://www.mdpi.com/2309-608X/8/3/294filamentous fungicytoskeletonmicrotubulesmotor moleculesintracellular transportnuclear division |
| spellingShingle | Marjatta Raudaskoski Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome Journal of Fungi filamentous fungi cytoskeleton microtubules motor molecules intracellular transport nuclear division |
| title | Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome |
| title_full | Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome |
| title_fullStr | Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome |
| title_full_unstemmed | Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome |
| title_short | Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome |
| title_sort | kinesin motors in the filamentous basidiomycetes in light of the i schizophyllum commune i genome |
| topic | filamentous fungi cytoskeleton microtubules motor molecules intracellular transport nuclear division |
| url | https://www.mdpi.com/2309-608X/8/3/294 |
| work_keys_str_mv | AT marjattaraudaskoski kinesinmotorsinthefilamentousbasidiomycetesinlightoftheischizophyllumcommuneigenome |