Antioxidant activity of glucosamine and its effects on ROS production, Nrf2, and O-GlcNAc expression in HMEC-1 cells

Antioxidant activity of glucosamine and its effects on ROS production, Nrf2, and O-GlcNAc expression in HMEC-1 cells

Glucosamine (GlcN) is the most used supplement for osteoarthritis treatment. In vitro studies have related GlcN to beneficial and detrimental effects on health. The aim of this study was to evaluate the effects of O-linked-N-acetylglucosaminylation (O-GlcNAc) on GlcN-induced ROS production and Nrf2...

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Bibliographic Details
Main Authors: B. Fernández-Rojas, T. Gómez-Sierra, O.N. Medina-Campos, J. Hernández-Juárez, P.A. Hernández-Cruz, I.B. Gallegos-Velasco, Y. Pérez-Cervera, J. Pedraza-Chaverri
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Toxicology
Subjects:
Glucosamine
ROS production
Nrf2
Endothelium
O-GlcNAc
Scavenging activity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X23000269

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http://www.sciencedirect.com/science/article/pii/S2666027X23000269

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