Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review
Docosahexaenoic acid (DHA), mainly found in microalgae and fish oil, is crucial for the growth and development of visual, neurological, and brain. In addition, DHA has been found to improve metabolic disorders associated with obesity and has anti-inflammatory, anti-obesity, and anti-adipogenesis eff...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/11/17/2685 |
| _version_ | 1797495432286306304 |
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| author | Wenwen Lv Duoxia Xu |
| author_facet | Wenwen Lv Duoxia Xu |
| author_sort | Wenwen Lv |
| collection | DOAJ |
| description | Docosahexaenoic acid (DHA), mainly found in microalgae and fish oil, is crucial for the growth and development of visual, neurological, and brain. In addition, DHA has been found to improve metabolic disorders associated with obesity and has anti-inflammatory, anti-obesity, and anti-adipogenesis effects. However, DHA applications in food are often limited due to its low water solubility, instability, and poor bioavailability. Therefore, delivery systems have been developed to enhance the remainder of DHA activity and increase DHA homeostasis and bioavailability. This review focused on the different DHA delivery systems and the in vitro and in vivo digestive characteristics. The research progress on cardiovascular diseases, diabetes, visual, neurological/brain, anti-obesity, anti-inflammatory, food applications, future trends, and the development potential of DHA delivery systems were also reviewed. DHA delivery systems could overcome the instability of DHA in gastrointestinal digestion, improve the bioavailability of DHA, and better play the role of its functionality. |
| first_indexed | 2024-03-10T01:49:31Z |
| format | Article |
| id | doaj.art-dea9c617968340f1afdd3bcdbe20af64 |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T01:49:31Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-dea9c617968340f1afdd3bcdbe20af642023-11-23T13:09:28ZengMDPI AGFoods2304-81582022-09-011117268510.3390/foods11172685Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A ReviewWenwen Lv0Duoxia Xu1Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, ChinaBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, ChinaDocosahexaenoic acid (DHA), mainly found in microalgae and fish oil, is crucial for the growth and development of visual, neurological, and brain. In addition, DHA has been found to improve metabolic disorders associated with obesity and has anti-inflammatory, anti-obesity, and anti-adipogenesis effects. However, DHA applications in food are often limited due to its low water solubility, instability, and poor bioavailability. Therefore, delivery systems have been developed to enhance the remainder of DHA activity and increase DHA homeostasis and bioavailability. This review focused on the different DHA delivery systems and the in vitro and in vivo digestive characteristics. The research progress on cardiovascular diseases, diabetes, visual, neurological/brain, anti-obesity, anti-inflammatory, food applications, future trends, and the development potential of DHA delivery systems were also reviewed. DHA delivery systems could overcome the instability of DHA in gastrointestinal digestion, improve the bioavailability of DHA, and better play the role of its functionality.https://www.mdpi.com/2304-8158/11/17/2685DHA delivery systemsdigestionbioavailabilityanti-obesityfood applications |
| spellingShingle | Wenwen Lv Duoxia Xu Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review Foods DHA delivery systems digestion bioavailability anti-obesity food applications |
| title | Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review |
| title_full | Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review |
| title_fullStr | Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review |
| title_full_unstemmed | Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review |
| title_short | Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review |
| title_sort | docosahexaenoic acid delivery systems bioavailability functionality and applications a review |
| topic | DHA delivery systems digestion bioavailability anti-obesity food applications |
| url | https://www.mdpi.com/2304-8158/11/17/2685 |
| work_keys_str_mv | AT wenwenlv docosahexaenoicaciddeliverysystemsbioavailabilityfunctionalityandapplicationsareview AT duoxiaxu docosahexaenoicaciddeliverysystemsbioavailabilityfunctionalityandapplicationsareview |