Deficiency of the lipid flippase ATP10A causes diet-induced dyslipidemia in female mice

Deficiency of the lipid flippase ATP10A causes diet-induced dyslipidemia in female mice

Abstract Genetic association studies have linked ATP10A and closely related type IV P-type ATPases (P4-ATPases) to insulin resistance and vascular complications, such as atherosclerosis. ATP10A translocates phosphatidylcholine and glucosylceramide across cell membranes, and these lipids or their met...

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Bibliographic Details
Main Authors: Adriana C. Norris, Eugenia M. Yazlovitskaya, Lin Zhu, Bailey S. Rose, Jody C. May, Katherine N. Gibson-Corley, John A. McLean, John M. Stafford, Todd R. Graham
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50360-5

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