Targeting reactive oxygen species and fat acid oxidation for the modulation of tumor-associated macrophages: a narrative review

Targeting reactive oxygen species and fat acid oxidation for the modulation of tumor-associated macrophages: a narrative review

Tumor-associated macrophages (TAMs) are significant immunocytes infiltrating the tumor microenvironment(TME). Recent research has shown that TAMs exhibit diversity in terms of their phenotype, function, time, and spatial distribution, which allows for further classification of TAM subtypes. The meta...

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Bibliographic Details
Main Authors: Yujian Teng, Licheng Xu, Wenjing Li, Pengyan Liu, Linli Tian, Ming Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
tumor-associated macrophages
reactive oxygen species
fatty acid oxidation
tumor microenvironment
recruitment
polarization
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1224443/full

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