A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i>
<em>Dendrophthoe falcata</em> (L.f.) Ettingsh is a hemiparasitic plant, used in Sri Lankan and Indian indigenous medicine to treat various diseases such as asthma, cancerous tumors, diabetes and wounds. Despite the hemiparasite on the host <em>Limonia acidissima</em> is used...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Faculty of Science, University of Peradeniya, Sri Lanka
2020-06-01
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| Series: | Ceylon Journal of Science |
| Subjects: | |
| Online Access: | https://cjs.sljol.info/articles/7736 |
| _version_ | 1811193721528516608 |
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| author | R.T. Karunaratne D.R. Uduwela |
| author_facet | R.T. Karunaratne D.R. Uduwela |
| author_sort | R.T. Karunaratne |
| collection | DOAJ |
| description | <em>Dendrophthoe falcata</em> (L.f.) Ettingsh is a hemiparasitic plant, used in Sri Lankan and Indian indigenous medicine to treat various diseases such as asthma, cancerous tumors, diabetes and wounds. Despite the hemiparasite on the host <em>Limonia acidissima</em> is used to treat various diseases, any bioactivity study of <em>Dendrophthoe falcata</em> grown on the particular host has not been conducted yet. This study aimed to investigate several bioactivities of the hemiparasite grown on <em>Limonia acidissima</em> (<em>La</em>) and compare with that grown on <em>Mangifera indica</em> (<em>Mi</em>). Sequential extracts by Soxhlet method from hexane (<em>La</em>-HE and <em>Mi</em>-HE), ethyl acetate (<em>La</em>-EAE and <em>Mi</em>-EAE) and methanol (<em>La</em>-ME and <em>Mi</em>-ME) were investigated for bioactivities. Antioxidant activity was determined using DPPH radical scavenging assay in which <em>Mi</em>-ME and <em>Mi</em>-EAE showed the highest activity, that is five times more than that of α-tocopherol. Brine shrimp lethality assay was conducted as a preliminary toxicity assay, where <em>La</em>-EAE showed the highest activity that is approximately four times that of K<sub>2</sub>Cr<sub>2</sub>O<sub>7</sub>. The total polyphenolic content was determined by Folin-Ciocalteu method in which both methanol extracts showed the highest polyphenolic content of which <em>Mi</em>-ME was approximately four times more than that of <em>La</em>-ME. These results suggest that the bioactivity of the hemiparasite vary considerably with the host. Further, extracts of the hemiparasite on <em>Limonia acidissima</em> showing high antioxidant activity coupled with high toxicity justifies its applicability in indigenous medicine. |
| first_indexed | 2024-04-12T00:13:10Z |
| format | Article |
| id | doaj.art-deb8c9e18dd74372947d144e670dd71d |
| institution | Directory Open Access Journal |
| issn | 2513-2814 2513-230X |
| language | English |
| last_indexed | 2024-04-12T00:13:10Z |
| publishDate | 2020-06-01 |
| publisher | Faculty of Science, University of Peradeniya, Sri Lanka |
| record_format | Article |
| series | Ceylon Journal of Science |
| spelling | doaj.art-deb8c9e18dd74372947d144e670dd71d2022-12-22T03:55:54ZengFaculty of Science, University of Peradeniya, Sri LankaCeylon Journal of Science2513-28142513-230X2020-06-0149215916410.4038/cjs.v49i2.77365803A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i>R.T. Karunaratne0D.R. Uduwela1University of PeradeniyaUniversity of Peradeniya<em>Dendrophthoe falcata</em> (L.f.) Ettingsh is a hemiparasitic plant, used in Sri Lankan and Indian indigenous medicine to treat various diseases such as asthma, cancerous tumors, diabetes and wounds. Despite the hemiparasite on the host <em>Limonia acidissima</em> is used to treat various diseases, any bioactivity study of <em>Dendrophthoe falcata</em> grown on the particular host has not been conducted yet. This study aimed to investigate several bioactivities of the hemiparasite grown on <em>Limonia acidissima</em> (<em>La</em>) and compare with that grown on <em>Mangifera indica</em> (<em>Mi</em>). Sequential extracts by Soxhlet method from hexane (<em>La</em>-HE and <em>Mi</em>-HE), ethyl acetate (<em>La</em>-EAE and <em>Mi</em>-EAE) and methanol (<em>La</em>-ME and <em>Mi</em>-ME) were investigated for bioactivities. Antioxidant activity was determined using DPPH radical scavenging assay in which <em>Mi</em>-ME and <em>Mi</em>-EAE showed the highest activity, that is five times more than that of α-tocopherol. Brine shrimp lethality assay was conducted as a preliminary toxicity assay, where <em>La</em>-EAE showed the highest activity that is approximately four times that of K<sub>2</sub>Cr<sub>2</sub>O<sub>7</sub>. The total polyphenolic content was determined by Folin-Ciocalteu method in which both methanol extracts showed the highest polyphenolic content of which <em>Mi</em>-ME was approximately four times more than that of <em>La</em>-ME. These results suggest that the bioactivity of the hemiparasite vary considerably with the host. Further, extracts of the hemiparasite on <em>Limonia acidissima</em> showing high antioxidant activity coupled with high toxicity justifies its applicability in indigenous medicine.https://cjs.sljol.info/articles/7736dendrophthoe falcatalimonia acidissimamangifera indicabioactivityhost dependence |
| spellingShingle | R.T. Karunaratne D.R. Uduwela A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i> Ceylon Journal of Science dendrophthoe falcata limonia acidissima mangifera indica bioactivity host dependence |
| title | A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i> |
| title_full | A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i> |
| title_fullStr | A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i> |
| title_full_unstemmed | A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i> |
| title_short | A comparison of the bioactivity of <i>Dendrophthoe falcata</i> on the hosts; <i>Limonia acidissima</i> and <i>Mangifera indica</i> |
| title_sort | comparison of the bioactivity of i dendrophthoe falcata i on the hosts i limonia acidissima i and i mangifera indica i |
| topic | dendrophthoe falcata limonia acidissima mangifera indica bioactivity host dependence |
| url | https://cjs.sljol.info/articles/7736 |
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