Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy
4 liters of polyethylene glycol (PEG) solution is commonly used to evacuate the colon before colonoscopy. This substance, however, is known to cause electrolyte abnormalities such as hyponatremia. Seizures caused by hyponatremia associated with bowel preparation have only rarely been reported. We re...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Kosin University College of Medicine
2012-12-01
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| Series: | Kosin Medical Journal |
| Subjects: | |
| Online Access: | http://www.kosinmedj.org/upload/pdf/ksmc027-02-14.pdf |
| _version_ | 1811192634839924736 |
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| author | Myung Hee Lee Byung Hee Lee Sook Kyung Oh Ji Young Seo Hyun Ju Kim Bo Jung Seo |
| author_facet | Myung Hee Lee Byung Hee Lee Sook Kyung Oh Ji Young Seo Hyun Ju Kim Bo Jung Seo |
| author_sort | Myung Hee Lee |
| collection | DOAJ |
| description | 4 liters of polyethylene glycol (PEG) solution is commonly used to evacuate the colon before colonoscopy. This substance, however, is known to cause electrolyte abnormalities such as hyponatremia. Seizures caused by hyponatremia associated with bowel preparation have only rarely been reported. We report the case that a 75-year-old woman with no prior history of seizures was developed severe hyponatremia (112 mEq/L) with generalized tonic-clonic seizure and mental change after ingestion of 4L of PEG solution. Past medical history was notable for thiazide diuretics. Her symptoms are improved during intravenous administration of hypertonic saline for the correction of hyponatremia. Patients with impaired ability to excrete free water those with renal insufficiency, hypothyroidism, mineralocorticoid deficiency, liver cirrhosis, or heart failure as well as those taking drugs which including thiazide diuretics, NASIDs, and ACE inhibitors have risk of hyponatremia following bowel preparation for colonoscopy. We conclude that physicians should check patient's condition and electrolyte abnormalities before colonoscopy procedures. |
| first_indexed | 2024-04-11T23:56:48Z |
| format | Article |
| id | doaj.art-deb96df0247e4e5387e721fdcf50229a |
| institution | Directory Open Access Journal |
| issn | 2005-9531 |
| language | English |
| last_indexed | 2024-04-11T23:56:48Z |
| publishDate | 2012-12-01 |
| publisher | Kosin University College of Medicine |
| record_format | Article |
| series | Kosin Medical Journal |
| spelling | doaj.art-deb96df0247e4e5387e721fdcf50229a2022-12-22T03:56:21ZengKosin University College of MedicineKosin Medical Journal2005-95312012-12-0127217317610.7180/kmj.2012.27.2.17313Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for ColonoscopyMyung Hee Lee0Byung Hee Lee1Sook Kyung Oh2Ji Young Seo3Hyun Ju Kim4Bo Jung Seo5Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.4 liters of polyethylene glycol (PEG) solution is commonly used to evacuate the colon before colonoscopy. This substance, however, is known to cause electrolyte abnormalities such as hyponatremia. Seizures caused by hyponatremia associated with bowel preparation have only rarely been reported. We report the case that a 75-year-old woman with no prior history of seizures was developed severe hyponatremia (112 mEq/L) with generalized tonic-clonic seizure and mental change after ingestion of 4L of PEG solution. Past medical history was notable for thiazide diuretics. Her symptoms are improved during intravenous administration of hypertonic saline for the correction of hyponatremia. Patients with impaired ability to excrete free water those with renal insufficiency, hypothyroidism, mineralocorticoid deficiency, liver cirrhosis, or heart failure as well as those taking drugs which including thiazide diuretics, NASIDs, and ACE inhibitors have risk of hyponatremia following bowel preparation for colonoscopy. We conclude that physicians should check patient's condition and electrolyte abnormalities before colonoscopy procedures.http://www.kosinmedj.org/upload/pdf/ksmc027-02-14.pdfcolonoscopyhyponatremiapolyethylene glycolseizure |
| spellingShingle | Myung Hee Lee Byung Hee Lee Sook Kyung Oh Ji Young Seo Hyun Ju Kim Bo Jung Seo Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy Kosin Medical Journal colonoscopy hyponatremia polyethylene glycol seizure |
| title | Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy |
| title_full | Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy |
| title_fullStr | Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy |
| title_full_unstemmed | Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy |
| title_short | Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy |
| title_sort | acute severe hyponatremia with seizure following polyethylene glycol based bowel preparation for colonoscopy |
| topic | colonoscopy hyponatremia polyethylene glycol seizure |
| url | http://www.kosinmedj.org/upload/pdf/ksmc027-02-14.pdf |
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