Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN Trial
The information available on the effects of maternal dietary habits on systemic inflammation and adverse maternal outcomes is limited. We aimed to evaluate whether Dietary Inflammatory Index (DII) score during pregnancy is associated with maternal body mass index (BMI), Mediterranean diet (MD) adher...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/11/2284 |
| _version_ | 1797492258491072512 |
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| author | Rosa Casas Sara Castro-Barquero Francesca Crovetto Marta Larroya Ana Maria Ruiz-León Laura Segalés Ayako Nakaki Lina Youssef Leticia Benitez Francesc Casanovas-Garriga Eduard Vieta Fàtima Crispi Eduard Gratacós Ramon Estruch |
| author_facet | Rosa Casas Sara Castro-Barquero Francesca Crovetto Marta Larroya Ana Maria Ruiz-León Laura Segalés Ayako Nakaki Lina Youssef Leticia Benitez Francesc Casanovas-Garriga Eduard Vieta Fàtima Crispi Eduard Gratacós Ramon Estruch |
| author_sort | Rosa Casas |
| collection | DOAJ |
| description | The information available on the effects of maternal dietary habits on systemic inflammation and adverse maternal outcomes is limited. We aimed to evaluate whether Dietary Inflammatory Index (DII) score during pregnancy is associated with maternal body mass index (BMI), Mediterranean diet (MD) adherence, and perinatal outcomes. At 19–23 weeks’ gestation, 1028 pregnant women were recruited. Dietary information was assessed using a 17-item dietary score to evaluate MD adherence and a validated 151-item food frequency questionnaire. DII score was established according to 33 food and nutritional proinflammatory and anti-inflammatory items. Participants were distributed into tertiles according to the DII score, where a lower DII score (first tertile) represented an anti-inflammatory diet and the third tertile represented the more proinflammatory diet. Maternal characteristics and perinatal outcomes were collected, and newborns’ birthweight percentiles were calculated. Adjusted logistic regression models were used to assess the association of the DII score with maternal and perinatal characteristics, setting the third tertile as the reference group. Women in the third tertile showed lower adherence to MD score compared to the first tertile: median (25th to 75th percentile) 9 (7 to 11) vs. 6 (4.25 to 8), <i>p</i> < 0.001. The proinflammatory diet was significantly associated with a higher maternal pre-pregnancy BMI (adjusted β = 0.88; 95% CI: 0.31 to 1.45) and lower newborn’s birthweight percentile (adjusted β = −9.84th; 95% CI: −19.6 to −0.12). These data show that a proinflammatory diet profile may be associated with maternal overweight and fetal undergrowth. |
| first_indexed | 2024-03-10T01:00:07Z |
| format | Article |
| id | doaj.art-deb9b2d80030461d9025fd0d33137521 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T01:00:07Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-deb9b2d80030461d9025fd0d331375212023-11-23T14:36:35ZengMDPI AGNutrients2072-66432022-05-011411228410.3390/nu14112284Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN TrialRosa Casas0Sara Castro-Barquero1Francesca Crovetto2Marta Larroya3Ana Maria Ruiz-León4Laura Segalés5Ayako Nakaki6Lina Youssef7Leticia Benitez8Francesc Casanovas-Garriga9Eduard Vieta10Fàtima Crispi11Eduard Gratacós12Ramon Estruch13Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERON), Instituto de Salud Carlos III, 28007 Madrid, SpainCentro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERON), Instituto de Salud Carlos III, 28007 Madrid, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainCentro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERON), Instituto de Salud Carlos III, 28007 Madrid, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainDepartment of Internal Medicine Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, 08028 Barcelona, SpainDepartment of Psychiatry and Psychology, Hospital Clinic, Neuroscience Institute, Institut d’Investigacions Biomèdiques August Pi i Sunyer, CIBERSAM, University of Barcelona, 08028 Barcelona, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainBCNatal|Fetal Medicine Research Center, Hospital Clínic and Hospital Sant Joan de Deéu, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08028 Barcelona, SpainCentro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERON), Instituto de Salud Carlos III, 28007 Madrid, SpainThe information available on the effects of maternal dietary habits on systemic inflammation and adverse maternal outcomes is limited. We aimed to evaluate whether Dietary Inflammatory Index (DII) score during pregnancy is associated with maternal body mass index (BMI), Mediterranean diet (MD) adherence, and perinatal outcomes. At 19–23 weeks’ gestation, 1028 pregnant women were recruited. Dietary information was assessed using a 17-item dietary score to evaluate MD adherence and a validated 151-item food frequency questionnaire. DII score was established according to 33 food and nutritional proinflammatory and anti-inflammatory items. Participants were distributed into tertiles according to the DII score, where a lower DII score (first tertile) represented an anti-inflammatory diet and the third tertile represented the more proinflammatory diet. Maternal characteristics and perinatal outcomes were collected, and newborns’ birthweight percentiles were calculated. Adjusted logistic regression models were used to assess the association of the DII score with maternal and perinatal characteristics, setting the third tertile as the reference group. Women in the third tertile showed lower adherence to MD score compared to the first tertile: median (25th to 75th percentile) 9 (7 to 11) vs. 6 (4.25 to 8), <i>p</i> < 0.001. The proinflammatory diet was significantly associated with a higher maternal pre-pregnancy BMI (adjusted β = 0.88; 95% CI: 0.31 to 1.45) and lower newborn’s birthweight percentile (adjusted β = −9.84th; 95% CI: −19.6 to −0.12). These data show that a proinflammatory diet profile may be associated with maternal overweight and fetal undergrowth.https://www.mdpi.com/2072-6643/14/11/2284Mediterranean dietDietary Inflammatory Indexpregnancybirthweight percentile |
| spellingShingle | Rosa Casas Sara Castro-Barquero Francesca Crovetto Marta Larroya Ana Maria Ruiz-León Laura Segalés Ayako Nakaki Lina Youssef Leticia Benitez Francesc Casanovas-Garriga Eduard Vieta Fàtima Crispi Eduard Gratacós Ramon Estruch Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN Trial Nutrients Mediterranean diet Dietary Inflammatory Index pregnancy birthweight percentile |
| title | Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN Trial |
| title_full | Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN Trial |
| title_fullStr | Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN Trial |
| title_full_unstemmed | Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN Trial |
| title_short | Maternal Dietary Inflammatory Index during Pregnancy Is Associated with Perinatal Outcomes: Results from the IMPACT BCN Trial |
| title_sort | maternal dietary inflammatory index during pregnancy is associated with perinatal outcomes results from the impact bcn trial |
| topic | Mediterranean diet Dietary Inflammatory Index pregnancy birthweight percentile |
| url | https://www.mdpi.com/2072-6643/14/11/2284 |
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