Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review

The term neurofibromatosis (NF) is used for a group of genetic disorders that primarily affect the cell growth of neural tissues. Neurofibromatosis type 1 (NF1), also known as von Recklinghausen′s disease, is the most common type of NF, and accounts for about 90% of all cases. It is one of the most...

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Main Authors: Parichehr Ghalayani, Zahra Saberi, Farimah Sardari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Dental Research Journal
Subjects:
Online Access:http://www.drjjournal.net/article.asp?issn=1735-3327;year=2012;volume=9;issue=4;spage=483;epage=488;aulast=Ghalayani
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author Parichehr Ghalayani
Zahra Saberi
Farimah Sardari
author_facet Parichehr Ghalayani
Zahra Saberi
Farimah Sardari
author_sort Parichehr Ghalayani
collection DOAJ
description The term neurofibromatosis (NF) is used for a group of genetic disorders that primarily affect the cell growth of neural tissues. Neurofibromatosis type 1 (NF1), also known as von Recklinghausen′s disease, is the most common type of NF, and accounts for about 90% of all cases. It is one of the most frequent human genetic diseases, with a prevalence of one case in 3,000 births. The expressivity of NF1 is extremely variable, with manifestations ranging from mild lesions to several complications and functional impairment. Oral manifestations can be found in almost 72% of the NF1 patients. The aim of this article is to report the NF1 in a family with different manifestations and to review the literature.
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spelling doaj.art-deba07a4d28c4c6e9b7f6738016e65102022-12-22T02:42:43ZengWolters Kluwer Medknow PublicationsDental Research Journal1735-33272008-02552012-01-019448348810.4103/1735-3327.102788Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature reviewParichehr GhalayaniZahra SaberiFarimah SardariThe term neurofibromatosis (NF) is used for a group of genetic disorders that primarily affect the cell growth of neural tissues. Neurofibromatosis type 1 (NF1), also known as von Recklinghausen′s disease, is the most common type of NF, and accounts for about 90% of all cases. It is one of the most frequent human genetic diseases, with a prevalence of one case in 3,000 births. The expressivity of NF1 is extremely variable, with manifestations ranging from mild lesions to several complications and functional impairment. Oral manifestations can be found in almost 72% of the NF1 patients. The aim of this article is to report the NF1 in a family with different manifestations and to review the literature.http://www.drjjournal.net/article.asp?issn=1735-3327;year=2012;volume=9;issue=4;spage=483;epage=488;aulast=GhalayaniGenetic diseasesneurofibromatosis type 1von Recklinghausen′s disease
spellingShingle Parichehr Ghalayani
Zahra Saberi
Farimah Sardari
Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review
Dental Research Journal
Genetic diseases
neurofibromatosis type 1
von Recklinghausen′s disease
title Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review
title_full Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review
title_fullStr Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review
title_full_unstemmed Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review
title_short Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review
title_sort neurofibromatosis type i von recklinghausen s disease a family case report and literature review
topic Genetic diseases
neurofibromatosis type 1
von Recklinghausen′s disease
url http://www.drjjournal.net/article.asp?issn=1735-3327;year=2012;volume=9;issue=4;spage=483;epage=488;aulast=Ghalayani
work_keys_str_mv AT parichehrghalayani neurofibromatosistypeivonrecklinghausensdiseaseafamilycasereportandliteraturereview
AT zahrasaberi neurofibromatosistypeivonrecklinghausensdiseaseafamilycasereportandliteraturereview
AT farimahsardari neurofibromatosistypeivonrecklinghausensdiseaseafamilycasereportandliteraturereview