Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review
The term neurofibromatosis (NF) is used for a group of genetic disorders that primarily affect the cell growth of neural tissues. Neurofibromatosis type 1 (NF1), also known as von Recklinghausen′s disease, is the most common type of NF, and accounts for about 90% of all cases. It is one of the most...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2012-01-01
|
Series: | Dental Research Journal |
Subjects: | |
Online Access: | http://www.drjjournal.net/article.asp?issn=1735-3327;year=2012;volume=9;issue=4;spage=483;epage=488;aulast=Ghalayani |
_version_ | 1811326288744415232 |
---|---|
author | Parichehr Ghalayani Zahra Saberi Farimah Sardari |
author_facet | Parichehr Ghalayani Zahra Saberi Farimah Sardari |
author_sort | Parichehr Ghalayani |
collection | DOAJ |
description | The term neurofibromatosis (NF) is used for a group of genetic disorders that primarily affect the cell growth of neural tissues. Neurofibromatosis type 1 (NF1), also known as von Recklinghausen′s disease, is the most common type of NF, and accounts for about 90% of all cases. It is one of the most frequent human genetic diseases, with a prevalence of one case in 3,000 births. The expressivity of NF1 is extremely variable, with manifestations ranging from mild lesions to several complications and functional impairment. Oral manifestations can be found in almost 72% of the NF1 patients. The aim of this article is to report the NF1 in a family with different manifestations and to review the literature. |
first_indexed | 2024-04-13T14:47:21Z |
format | Article |
id | doaj.art-deba07a4d28c4c6e9b7f6738016e6510 |
institution | Directory Open Access Journal |
issn | 1735-3327 2008-0255 |
language | English |
last_indexed | 2024-04-13T14:47:21Z |
publishDate | 2012-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Dental Research Journal |
spelling | doaj.art-deba07a4d28c4c6e9b7f6738016e65102022-12-22T02:42:43ZengWolters Kluwer Medknow PublicationsDental Research Journal1735-33272008-02552012-01-019448348810.4103/1735-3327.102788Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature reviewParichehr GhalayaniZahra SaberiFarimah SardariThe term neurofibromatosis (NF) is used for a group of genetic disorders that primarily affect the cell growth of neural tissues. Neurofibromatosis type 1 (NF1), also known as von Recklinghausen′s disease, is the most common type of NF, and accounts for about 90% of all cases. It is one of the most frequent human genetic diseases, with a prevalence of one case in 3,000 births. The expressivity of NF1 is extremely variable, with manifestations ranging from mild lesions to several complications and functional impairment. Oral manifestations can be found in almost 72% of the NF1 patients. The aim of this article is to report the NF1 in a family with different manifestations and to review the literature.http://www.drjjournal.net/article.asp?issn=1735-3327;year=2012;volume=9;issue=4;spage=483;epage=488;aulast=GhalayaniGenetic diseasesneurofibromatosis type 1von Recklinghausen′s disease |
spellingShingle | Parichehr Ghalayani Zahra Saberi Farimah Sardari Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review Dental Research Journal Genetic diseases neurofibromatosis type 1 von Recklinghausen′s disease |
title | Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review |
title_full | Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review |
title_fullStr | Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review |
title_full_unstemmed | Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review |
title_short | Neurofibromatosis type I (von Recklinghausen′s disease): A family case report and literature review |
title_sort | neurofibromatosis type i von recklinghausen s disease a family case report and literature review |
topic | Genetic diseases neurofibromatosis type 1 von Recklinghausen′s disease |
url | http://www.drjjournal.net/article.asp?issn=1735-3327;year=2012;volume=9;issue=4;spage=483;epage=488;aulast=Ghalayani |
work_keys_str_mv | AT parichehrghalayani neurofibromatosistypeivonrecklinghausensdiseaseafamilycasereportandliteraturereview AT zahrasaberi neurofibromatosistypeivonrecklinghausensdiseaseafamilycasereportandliteraturereview AT farimahsardari neurofibromatosistypeivonrecklinghausensdiseaseafamilycasereportandliteraturereview |