Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer
Abstract Background There have been several reports demonstrating the safety of flexible bronchoscopy (FB) in the elderly, but none have focused specifically on lung cancer, which is a frequent biopsy procedure. Methods In this study, we retrospectively evaluated the safety of FB and subsequent trea...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-03-01
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| Series: | Thoracic Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1759-7714.15228 |
| _version_ | 1797265490902515712 |
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| author | Zentaro Saito Issei Oi Takanori Ito Takuma Imakita Osamu Kanai Kohei Fujita Tadashi Mio |
| author_facet | Zentaro Saito Issei Oi Takanori Ito Takuma Imakita Osamu Kanai Kohei Fujita Tadashi Mio |
| author_sort | Zentaro Saito |
| collection | DOAJ |
| description | Abstract Background There have been several reports demonstrating the safety of flexible bronchoscopy (FB) in the elderly, but none have focused specifically on lung cancer, which is a frequent biopsy procedure. Methods In this study, we retrospectively evaluated the safety of FB and subsequent treatment in elderly patients with suspected primary lung cancer. Elderly patients were defined as 75 years of age or older. Results A total of 141 patients, 77 in the elderly group and 64 in the nonelderly group, were reviewed. The median age of the elderly group was 80 years. Transbronchial lung biopsy was performed in more than 80% of all patients. Primary lung cancer was diagnosed in 42 (54.4%) of the elderly group and 35 (54.7%) of the nonelderly group (p = 0.38). Approximately 70% of the elderly patients with a confirmed diagnosis were treated, while more than half of the undiagnosed elderly patients had best supportive care. Complications such as bleeding, pneumothorax, fever, and pneumonia were similar in the elderly and nonelderly groups. Conclusions This study suggests that flexible bronchoscopy can be performed as safely in the elderly as in the nonelderly. Furthermore, even elderly patients may have a greater chance of receiving treatment when a definitive diagnosis is achieved. |
| first_indexed | 2024-04-25T00:45:38Z |
| format | Article |
| id | doaj.art-debaad9273ca4a38afe3a6f95ff053bb |
| institution | Directory Open Access Journal |
| issn | 1759-7706 1759-7714 |
| language | English |
| last_indexed | 2024-04-25T00:45:38Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj.art-debaad9273ca4a38afe3a6f95ff053bb2024-03-12T05:30:58ZengWileyThoracic Cancer1759-77061759-77142024-03-0115861462110.1111/1759-7714.15228Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancerZentaro Saito0Issei Oi1Takanori Ito2Takuma Imakita3Osamu Kanai4Kohei Fujita5Tadashi Mio6Division of Respiratory Medicine National Hospital Organization Kyoto Medical Center Kyoto JapanDivision of Respiratory Medicine National Hospital Organization Kyoto Medical Center Kyoto JapanDivision of Respiratory Medicine National Hospital Organization Kyoto Medical Center Kyoto JapanDivision of Respiratory Medicine National Hospital Organization Kyoto Medical Center Kyoto JapanDivision of Respiratory Medicine National Hospital Organization Kyoto Medical Center Kyoto JapanDivision of Respiratory Medicine National Hospital Organization Kyoto Medical Center Kyoto JapanDivision of Respiratory Medicine National Hospital Organization Kyoto Medical Center Kyoto JapanAbstract Background There have been several reports demonstrating the safety of flexible bronchoscopy (FB) in the elderly, but none have focused specifically on lung cancer, which is a frequent biopsy procedure. Methods In this study, we retrospectively evaluated the safety of FB and subsequent treatment in elderly patients with suspected primary lung cancer. Elderly patients were defined as 75 years of age or older. Results A total of 141 patients, 77 in the elderly group and 64 in the nonelderly group, were reviewed. The median age of the elderly group was 80 years. Transbronchial lung biopsy was performed in more than 80% of all patients. Primary lung cancer was diagnosed in 42 (54.4%) of the elderly group and 35 (54.7%) of the nonelderly group (p = 0.38). Approximately 70% of the elderly patients with a confirmed diagnosis were treated, while more than half of the undiagnosed elderly patients had best supportive care. Complications such as bleeding, pneumothorax, fever, and pneumonia were similar in the elderly and nonelderly groups. Conclusions This study suggests that flexible bronchoscopy can be performed as safely in the elderly as in the nonelderly. Furthermore, even elderly patients may have a greater chance of receiving treatment when a definitive diagnosis is achieved.https://doi.org/10.1111/1759-7714.15228elderlyflexible bronchoscopylung cancer |
| spellingShingle | Zentaro Saito Issei Oi Takanori Ito Takuma Imakita Osamu Kanai Kohei Fujita Tadashi Mio Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer Thoracic Cancer elderly flexible bronchoscopy lung cancer |
| title | Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer |
| title_full | Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer |
| title_fullStr | Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer |
| title_full_unstemmed | Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer |
| title_short | Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer |
| title_sort | safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer |
| topic | elderly flexible bronchoscopy lung cancer |
| url | https://doi.org/10.1111/1759-7714.15228 |
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