A rare case of tumefactive demyelination of brain: A case report and literature review
Abstract This case report highlights the diagnostic challenges encountered in a 30‐year‐old female presenting with fever followed by Wernicke's aphasia without right‐sided weakness, ultimately diagnosed as tumefactive demyelination (TD). TD is a rare neurological condition often misidentified a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-12-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8369 |
| _version_ | 1797372111352758272 |
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| author | Pugazhendi Inban Ogbonnaya Akuma Zenia Elavia Chinaza Mercy Akuma Mansi Singh Meet Popatbhai Kachhadia Agaba Barnett James Musiime |
| author_facet | Pugazhendi Inban Ogbonnaya Akuma Zenia Elavia Chinaza Mercy Akuma Mansi Singh Meet Popatbhai Kachhadia Agaba Barnett James Musiime |
| author_sort | Pugazhendi Inban |
| collection | DOAJ |
| description | Abstract This case report highlights the diagnostic challenges encountered in a 30‐year‐old female presenting with fever followed by Wernicke's aphasia without right‐sided weakness, ultimately diagnosed as tumefactive demyelination (TD). TD is a rare neurological condition often misidentified as brain tumors or inflammatory disorders. The case emphasizes the importance of precise differentiation through advanced magnetic resonance imaging, showing restricted diffusion at lesion edges and the absence of gadolinium enhancement. Accurate diagnosis is crucial for tailored treatment and prognostic assessment. This case contributes to our understanding of TD and underscores the need for continued research and collaboration in the field of rare neurological disorders. |
| first_indexed | 2024-03-08T18:31:08Z |
| format | Article |
| id | doaj.art-debb6f6acb9a4af7bdde34f7f4cb7405 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-08T18:31:08Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-debb6f6acb9a4af7bdde34f7f4cb74052023-12-30T04:35:09ZengWileyClinical Case Reports2050-09042023-12-011112n/an/a10.1002/ccr3.8369A rare case of tumefactive demyelination of brain: A case report and literature reviewPugazhendi Inban0Ogbonnaya Akuma1Zenia Elavia2Chinaza Mercy Akuma3Mansi Singh4Meet Popatbhai Kachhadia5Agaba Barnett James Musiime6Department of General Medicine Government Medical College Chennai IndiaEbonyi State University Abakaliki NigeriaDr. DY Patil Medical College Pune IndiaNnamdi Azikiwe University Awka NigeriaBogomolets National Medical University Kyiv UkraineP.D.U Medical College, Civil Hospital Campus Rajkot IndiaRoyal College of General Practitioners (RCGP) London UKAbstract This case report highlights the diagnostic challenges encountered in a 30‐year‐old female presenting with fever followed by Wernicke's aphasia without right‐sided weakness, ultimately diagnosed as tumefactive demyelination (TD). TD is a rare neurological condition often misidentified as brain tumors or inflammatory disorders. The case emphasizes the importance of precise differentiation through advanced magnetic resonance imaging, showing restricted diffusion at lesion edges and the absence of gadolinium enhancement. Accurate diagnosis is crucial for tailored treatment and prognostic assessment. This case contributes to our understanding of TD and underscores the need for continued research and collaboration in the field of rare neurological disorders.https://doi.org/10.1002/ccr3.8369cerebral spinal fluid (CSF)magnetic resonance imaging (MRI)magnetic resonance spectroscopy (MRS)multiple sclerosistumefactive demyelination (TD)Wernicke's aphasia |
| spellingShingle | Pugazhendi Inban Ogbonnaya Akuma Zenia Elavia Chinaza Mercy Akuma Mansi Singh Meet Popatbhai Kachhadia Agaba Barnett James Musiime A rare case of tumefactive demyelination of brain: A case report and literature review Clinical Case Reports cerebral spinal fluid (CSF) magnetic resonance imaging (MRI) magnetic resonance spectroscopy (MRS) multiple sclerosis tumefactive demyelination (TD) Wernicke's aphasia |
| title | A rare case of tumefactive demyelination of brain: A case report and literature review |
| title_full | A rare case of tumefactive demyelination of brain: A case report and literature review |
| title_fullStr | A rare case of tumefactive demyelination of brain: A case report and literature review |
| title_full_unstemmed | A rare case of tumefactive demyelination of brain: A case report and literature review |
| title_short | A rare case of tumefactive demyelination of brain: A case report and literature review |
| title_sort | rare case of tumefactive demyelination of brain a case report and literature review |
| topic | cerebral spinal fluid (CSF) magnetic resonance imaging (MRI) magnetic resonance spectroscopy (MRS) multiple sclerosis tumefactive demyelination (TD) Wernicke's aphasia |
| url | https://doi.org/10.1002/ccr3.8369 |
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