Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)
Abstract Background This study aimed to compare the visual outcomes of the first operated eyes with those of the second operated eyes following small-incision lenticule extraction (SMILE). Methods A total of 202 patients (404 eyes) underwent SMILE using the tear film mark centration method for myopi...
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BMC
2024-04-01
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Series: | BMC Ophthalmology |
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Online Access: | https://doi.org/10.1186/s12886-024-03414-9 |
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author | Anzhen Li Xiaowei Yang Wei Wang Wenbin Huang Hui Ding Ke Nie Tan Zhong Shisi Hu Zhenduo Yang Xingwu Zhong |
author_facet | Anzhen Li Xiaowei Yang Wei Wang Wenbin Huang Hui Ding Ke Nie Tan Zhong Shisi Hu Zhenduo Yang Xingwu Zhong |
author_sort | Anzhen Li |
collection | DOAJ |
description | Abstract Background This study aimed to compare the visual outcomes of the first operated eyes with those of the second operated eyes following small-incision lenticule extraction (SMILE). Methods A total of 202 patients (404 eyes) underwent SMILE using the tear film mark centration method for myopia and myopic astigmatism correction. Baseline characteristics, objective optical quality, decentered displacement, induced corneal aberrations, and modulation transfer function (MTF) values were assessed. Linear regression analyzed the relationship between decentration and visual quality parameters, including corneal aberrations and MTF values. Results No significant difference was observed in objective visual quality, efficacy, and safety indexes between the two groups (all P > 0.05). The average decentered displacement for the first and second surgical eyes was 0.278 ± 0.17 mm and 0.315 ± 0.15 mm, respectively (P = 0.002). The horizontal coma in the first surgical eyes were notably lower than in the second (P = 0.000). MTF values at spatial frequencies of 5, 10, 15, and 20 cycles/degree (c/d) were higher in the first surgical eyes compared to the second (all P < 0.05). Linear regression indicated that high-order aberrations (HOAs), root mean square (RMS) coma, spherical aberration, horizontal coma, vertical coma, and eccentric displacement were all linearly correlated. Furthermore, MTF values exhibited a linear relationship with eccentric displacement across these spatial frequencies. Conclusions There was no discernible difference in visual acuity, efficacy, or safety between the two operated eyes. Nonetheless, the first operated eyes exhibited reduced decentered displacement and demonstrated superior outcomes in terms of horizontal coma and MTF values compared to the second operated eyes following SMILE. The variations in visual quality parameters were linearly correlated with decentered displacement. |
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language | English |
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series | BMC Ophthalmology |
spelling | doaj.art-debd09ef5e4e4ffb9e36228e029492642024-04-14T11:10:35ZengBMCBMC Ophthalmology1471-24152024-04-0124111010.1186/s12886-024-03414-9Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)Anzhen Li0Xiaowei Yang1Wei Wang2Wenbin Huang3Hui Ding4Ke Nie5Tan Zhong6Shisi Hu7Zhenduo Yang8Xingwu Zhong9State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesAbstract Background This study aimed to compare the visual outcomes of the first operated eyes with those of the second operated eyes following small-incision lenticule extraction (SMILE). Methods A total of 202 patients (404 eyes) underwent SMILE using the tear film mark centration method for myopia and myopic astigmatism correction. Baseline characteristics, objective optical quality, decentered displacement, induced corneal aberrations, and modulation transfer function (MTF) values were assessed. Linear regression analyzed the relationship between decentration and visual quality parameters, including corneal aberrations and MTF values. Results No significant difference was observed in objective visual quality, efficacy, and safety indexes between the two groups (all P > 0.05). The average decentered displacement for the first and second surgical eyes was 0.278 ± 0.17 mm and 0.315 ± 0.15 mm, respectively (P = 0.002). The horizontal coma in the first surgical eyes were notably lower than in the second (P = 0.000). MTF values at spatial frequencies of 5, 10, 15, and 20 cycles/degree (c/d) were higher in the first surgical eyes compared to the second (all P < 0.05). Linear regression indicated that high-order aberrations (HOAs), root mean square (RMS) coma, spherical aberration, horizontal coma, vertical coma, and eccentric displacement were all linearly correlated. Furthermore, MTF values exhibited a linear relationship with eccentric displacement across these spatial frequencies. Conclusions There was no discernible difference in visual acuity, efficacy, or safety between the two operated eyes. Nonetheless, the first operated eyes exhibited reduced decentered displacement and demonstrated superior outcomes in terms of horizontal coma and MTF values compared to the second operated eyes following SMILE. The variations in visual quality parameters were linearly correlated with decentered displacement.https://doi.org/10.1186/s12886-024-03414-9SMILESurgical sequenceLenticule decentrationHigh-order-aberrationModulation transfer function |
spellingShingle | Anzhen Li Xiaowei Yang Wei Wang Wenbin Huang Hui Ding Ke Nie Tan Zhong Shisi Hu Zhenduo Yang Xingwu Zhong Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE) BMC Ophthalmology SMILE Surgical sequence Lenticule decentration High-order-aberration Modulation transfer function |
title | Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE) |
title_full | Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE) |
title_fullStr | Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE) |
title_full_unstemmed | Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE) |
title_short | Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE) |
title_sort | comparative visual outcomes of the first versus second eye following small incision lenticule extraction smile |
topic | SMILE Surgical sequence Lenticule decentration High-order-aberration Modulation transfer function |
url | https://doi.org/10.1186/s12886-024-03414-9 |
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