Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)

Abstract Background This study aimed to compare the visual outcomes of the first operated eyes with those of the second operated eyes following small-incision lenticule extraction (SMILE). Methods A total of 202 patients (404 eyes) underwent SMILE using the tear film mark centration method for myopi...

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Main Authors: Anzhen Li, Xiaowei Yang, Wei Wang, Wenbin Huang, Hui Ding, Ke Nie, Tan Zhong, Shisi Hu, Zhenduo Yang, Xingwu Zhong
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-024-03414-9
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author Anzhen Li
Xiaowei Yang
Wei Wang
Wenbin Huang
Hui Ding
Ke Nie
Tan Zhong
Shisi Hu
Zhenduo Yang
Xingwu Zhong
author_facet Anzhen Li
Xiaowei Yang
Wei Wang
Wenbin Huang
Hui Ding
Ke Nie
Tan Zhong
Shisi Hu
Zhenduo Yang
Xingwu Zhong
author_sort Anzhen Li
collection DOAJ
description Abstract Background This study aimed to compare the visual outcomes of the first operated eyes with those of the second operated eyes following small-incision lenticule extraction (SMILE). Methods A total of 202 patients (404 eyes) underwent SMILE using the tear film mark centration method for myopia and myopic astigmatism correction. Baseline characteristics, objective optical quality, decentered displacement, induced corneal aberrations, and modulation transfer function (MTF) values were assessed. Linear regression analyzed the relationship between decentration and visual quality parameters, including corneal aberrations and MTF values. Results No significant difference was observed in objective visual quality, efficacy, and safety indexes between the two groups (all P > 0.05). The average decentered displacement for the first and second surgical eyes was 0.278 ± 0.17 mm and 0.315 ± 0.15 mm, respectively (P = 0.002). The horizontal coma in the first surgical eyes were notably lower than in the second (P = 0.000). MTF values at spatial frequencies of 5, 10, 15, and 20 cycles/degree (c/d) were higher in the first surgical eyes compared to the second (all P < 0.05). Linear regression indicated that high-order aberrations (HOAs), root mean square (RMS) coma, spherical aberration, horizontal coma, vertical coma, and eccentric displacement were all linearly correlated. Furthermore, MTF values exhibited a linear relationship with eccentric displacement across these spatial frequencies. Conclusions There was no discernible difference in visual acuity, efficacy, or safety between the two operated eyes. Nonetheless, the first operated eyes exhibited reduced decentered displacement and demonstrated superior outcomes in terms of horizontal coma and MTF values compared to the second operated eyes following SMILE. The variations in visual quality parameters were linearly correlated with decentered displacement.
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spelling doaj.art-debd09ef5e4e4ffb9e36228e029492642024-04-14T11:10:35ZengBMCBMC Ophthalmology1471-24152024-04-0124111010.1186/s12886-024-03414-9Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)Anzhen Li0Xiaowei Yang1Wei Wang2Wenbin Huang3Hui Ding4Ke Nie5Tan Zhong6Shisi Hu7Zhenduo Yang8Xingwu Zhong9State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityHainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Guangdong Provincial Clinical Research Center for Ocular DiseasesAbstract Background This study aimed to compare the visual outcomes of the first operated eyes with those of the second operated eyes following small-incision lenticule extraction (SMILE). Methods A total of 202 patients (404 eyes) underwent SMILE using the tear film mark centration method for myopia and myopic astigmatism correction. Baseline characteristics, objective optical quality, decentered displacement, induced corneal aberrations, and modulation transfer function (MTF) values were assessed. Linear regression analyzed the relationship between decentration and visual quality parameters, including corneal aberrations and MTF values. Results No significant difference was observed in objective visual quality, efficacy, and safety indexes between the two groups (all P > 0.05). The average decentered displacement for the first and second surgical eyes was 0.278 ± 0.17 mm and 0.315 ± 0.15 mm, respectively (P = 0.002). The horizontal coma in the first surgical eyes were notably lower than in the second (P = 0.000). MTF values at spatial frequencies of 5, 10, 15, and 20 cycles/degree (c/d) were higher in the first surgical eyes compared to the second (all P < 0.05). Linear regression indicated that high-order aberrations (HOAs), root mean square (RMS) coma, spherical aberration, horizontal coma, vertical coma, and eccentric displacement were all linearly correlated. Furthermore, MTF values exhibited a linear relationship with eccentric displacement across these spatial frequencies. Conclusions There was no discernible difference in visual acuity, efficacy, or safety between the two operated eyes. Nonetheless, the first operated eyes exhibited reduced decentered displacement and demonstrated superior outcomes in terms of horizontal coma and MTF values compared to the second operated eyes following SMILE. The variations in visual quality parameters were linearly correlated with decentered displacement.https://doi.org/10.1186/s12886-024-03414-9SMILESurgical sequenceLenticule decentrationHigh-order-aberrationModulation transfer function
spellingShingle Anzhen Li
Xiaowei Yang
Wei Wang
Wenbin Huang
Hui Ding
Ke Nie
Tan Zhong
Shisi Hu
Zhenduo Yang
Xingwu Zhong
Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)
BMC Ophthalmology
SMILE
Surgical sequence
Lenticule decentration
High-order-aberration
Modulation transfer function
title Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)
title_full Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)
title_fullStr Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)
title_full_unstemmed Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)
title_short Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE)
title_sort comparative visual outcomes of the first versus second eye following small incision lenticule extraction smile
topic SMILE
Surgical sequence
Lenticule decentration
High-order-aberration
Modulation transfer function
url https://doi.org/10.1186/s12886-024-03414-9
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