Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?

Nutrition therapy plays an integral role in the prevention and management of patients with type 2 diabetes (T2D). A potential strategy is the utilization of diabetes-specific nutrition formulas (DSNFs) as meal replacements. In this article, we distinguish DSNFs from standard nutrition formulas, revi...

Full description

Bibliographic Details
Main Authors: Jarvis C. Noronha, Jeffrey I. Mechanick
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.874968/full
_version_ 1811303647611453440
author Jarvis C. Noronha
Jarvis C. Noronha
Jeffrey I. Mechanick
author_facet Jarvis C. Noronha
Jarvis C. Noronha
Jeffrey I. Mechanick
author_sort Jarvis C. Noronha
collection DOAJ
description Nutrition therapy plays an integral role in the prevention and management of patients with type 2 diabetes (T2D). A potential strategy is the utilization of diabetes-specific nutrition formulas (DSNFs) as meal replacements. In this article, we distinguish DSNFs from standard nutrition formulas, review the clinical data examining the effectiveness of DSNFs, and propose an evidence-based algorithm for incorporating DSNFs as part of nutrition therapy in T2D. DSNFs contain slowly-digestible carbohydrates, healthy fats (e.g., monounsaturated fatty acids), and specific micronutrients, which provide added benefits over standard nutrition formulas. In short- and long-term clinical trials, DSNFs demonstrate improvements in postprandial glycemic responses translating into sustainable benefits in long-term glycemic control (e.g., hemoglobin A1c and glycemic variability) and various cardiometabolic outcomes. To facilitate the delivery of DSNFs in a clinical setting, the transcultural diabetes nutrition algorithm can be utilized based on body weight (underweight, normal weight, or overweight) and level of glycemic control (controlled or uncontrolled).
first_indexed 2024-04-13T07:51:55Z
format Article
id doaj.art-dec02bfec8804b7bbc5f39239e784f3b
institution Directory Open Access Journal
issn 1664-2392
language English
last_indexed 2024-04-13T07:51:55Z
publishDate 2022-04-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Endocrinology
spelling doaj.art-dec02bfec8804b7bbc5f39239e784f3b2022-12-22T02:55:30ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-04-011310.3389/fendo.2022.874968874968Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?Jarvis C. Noronha0Jarvis C. Noronha1Jeffrey I. Mechanick2Toronto 3D (Diet, Digestive Tract and Disease) Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, St. Michael’s Hospital, Toronto, ON, CanadaSchool of Medicine, Faculty of Medicine, The University of Queensland, Brisbane, QLD, AustraliaMarie-Josée and Henry R. Kravis Center for Cardiovascular Health at Mount Sinai Heart, and Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesNutrition therapy plays an integral role in the prevention and management of patients with type 2 diabetes (T2D). A potential strategy is the utilization of diabetes-specific nutrition formulas (DSNFs) as meal replacements. In this article, we distinguish DSNFs from standard nutrition formulas, review the clinical data examining the effectiveness of DSNFs, and propose an evidence-based algorithm for incorporating DSNFs as part of nutrition therapy in T2D. DSNFs contain slowly-digestible carbohydrates, healthy fats (e.g., monounsaturated fatty acids), and specific micronutrients, which provide added benefits over standard nutrition formulas. In short- and long-term clinical trials, DSNFs demonstrate improvements in postprandial glycemic responses translating into sustainable benefits in long-term glycemic control (e.g., hemoglobin A1c and glycemic variability) and various cardiometabolic outcomes. To facilitate the delivery of DSNFs in a clinical setting, the transcultural diabetes nutrition algorithm can be utilized based on body weight (underweight, normal weight, or overweight) and level of glycemic control (controlled or uncontrolled).https://www.frontiersin.org/articles/10.3389/fendo.2022.874968/fullmeal replacementglycemic responseglycemic controldiabetesclinical practice
spellingShingle Jarvis C. Noronha
Jarvis C. Noronha
Jeffrey I. Mechanick
Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?
Frontiers in Endocrinology
meal replacement
glycemic response
glycemic control
diabetes
clinical practice
title Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?
title_full Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?
title_fullStr Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?
title_full_unstemmed Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?
title_short Is There a Role for Diabetes-Specific Nutrition Formulas as Meal Replacements in Type 2 Diabetes?
title_sort is there a role for diabetes specific nutrition formulas as meal replacements in type 2 diabetes
topic meal replacement
glycemic response
glycemic control
diabetes
clinical practice
url https://www.frontiersin.org/articles/10.3389/fendo.2022.874968/full
work_keys_str_mv AT jarviscnoronha istherearolefordiabetesspecificnutritionformulasasmealreplacementsintype2diabetes
AT jarviscnoronha istherearolefordiabetesspecificnutritionformulasasmealreplacementsintype2diabetes
AT jeffreyimechanick istherearolefordiabetesspecificnutritionformulasasmealreplacementsintype2diabetes