Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report
Abstract Background Despite the high prevalence of locally advanced head and neck cancer, treatment failure in the form of a cutaneous deposit in the treatment field during radiation is not common. There has never been a cytology-proven published case of marginal treatment failure in the cutaneous r...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-03-01
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| Series: | The Egyptian Journal of Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43163-023-00401-7 |
| _version_ | 1827267309808386048 |
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| author | Debanjan Sikdar Sweety Gupta Abhishek Charavarty Bhoomika Kaushik Deepa M. Joseph Manoj Gupta |
| author_facet | Debanjan Sikdar Sweety Gupta Abhishek Charavarty Bhoomika Kaushik Deepa M. Joseph Manoj Gupta |
| author_sort | Debanjan Sikdar |
| collection | DOAJ |
| description | Abstract Background Despite the high prevalence of locally advanced head and neck cancer, treatment failure in the form of a cutaneous deposit in the treatment field during radiation is not common. There has never been a cytology-proven published case of marginal treatment failure in the cutaneous region during radiotherapy. Case presentation A 51-year-old male patient was diagnosed with squamous cell carcinoma of the left tonsillar fossa. After a partial response to induction chemotherapy, the patient was treated with definitive chemo-radiotherapy. After the 23rd fractionation of radiotherapy, there was a clinical progression in the form of a solitary skin nodule within the treatment field, which was further treated with an electron boost to a total dose of 70 Gy followed by palliative chemotherapy. Conclusion During definitive chemoradiotherapy, failure outside the high-dose radiation field is not common, and a skin nodule during treatment had never been described. Our case demonstrates the importance of performing thorough clinical examinations on a weekly basis, not only for toxicity assessment but also for treatment response. |
| first_indexed | 2024-04-09T23:13:32Z |
| format | Article |
| id | doaj.art-dec19759d0744ead9a1cacf5b18541d1 |
| institution | Directory Open Access Journal |
| issn | 2090-8539 |
| language | English |
| last_indexed | 2025-03-22T04:31:42Z |
| publishDate | 2023-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Otolaryngology |
| spelling | doaj.art-dec19759d0744ead9a1cacf5b18541d12024-04-28T03:45:13ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392023-03-013911410.1186/s43163-023-00401-7Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case reportDebanjan Sikdar0Sweety Gupta1Abhishek Charavarty2Bhoomika Kaushik3Deepa M. Joseph4Manoj Gupta5Radiation Oncology, AIIMS RishikeshRadiation Oncology, AIIMS RishikeshRadiation Oncology, AIIMS RishikeshPathology, AIIMS RishikeshRadiation Oncology, AIIMS RishikeshRadiation Oncology, AIIMS RishikeshAbstract Background Despite the high prevalence of locally advanced head and neck cancer, treatment failure in the form of a cutaneous deposit in the treatment field during radiation is not common. There has never been a cytology-proven published case of marginal treatment failure in the cutaneous region during radiotherapy. Case presentation A 51-year-old male patient was diagnosed with squamous cell carcinoma of the left tonsillar fossa. After a partial response to induction chemotherapy, the patient was treated with definitive chemo-radiotherapy. After the 23rd fractionation of radiotherapy, there was a clinical progression in the form of a solitary skin nodule within the treatment field, which was further treated with an electron boost to a total dose of 70 Gy followed by palliative chemotherapy. Conclusion During definitive chemoradiotherapy, failure outside the high-dose radiation field is not common, and a skin nodule during treatment had never been described. Our case demonstrates the importance of performing thorough clinical examinations on a weekly basis, not only for toxicity assessment but also for treatment response.https://doi.org/10.1186/s43163-023-00401-7Head and neck cancerTreatment failureSkin depositOut-of-field failure |
| spellingShingle | Debanjan Sikdar Sweety Gupta Abhishek Charavarty Bhoomika Kaushik Deepa M. Joseph Manoj Gupta Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report The Egyptian Journal of Otolaryngology Head and neck cancer Treatment failure Skin deposit Out-of-field failure |
| title | Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report |
| title_full | Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report |
| title_fullStr | Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report |
| title_full_unstemmed | Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report |
| title_short | Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report |
| title_sort | managing unpredictable challenge of a metastatic nodule in radiation treatment field a case report |
| topic | Head and neck cancer Treatment failure Skin deposit Out-of-field failure |
| url | https://doi.org/10.1186/s43163-023-00401-7 |
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