RESISTANT ARTERIAL HYPERTENSION

Resistant hypertension is defined as a lack to lower 140 mmHg (systolic blood pressure) and 90 mmHg (diastolic blood pressure) values of ambulatory blood pressure (BP) response using 3 antihypertensive agents of different classes, one of which should be a diuretic in patients fully adherent to antih...

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Main Authors: T. E. Esaulova, A. V. Aksenova, O. A. Sivakova, I. Ye. Chazova
Format: Article
Language:Russian
Published: InterMedservice 2018-09-01
Series:Евразийский Кардиологический Журнал
Subjects:
Online Access:https://www.heartj.asia/jour/article/view/301
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author T. E. Esaulova
A. V. Aksenova
O. A. Sivakova
I. Ye. Chazova
author_facet T. E. Esaulova
A. V. Aksenova
O. A. Sivakova
I. Ye. Chazova
author_sort T. E. Esaulova
collection DOAJ
description Resistant hypertension is defined as a lack to lower 140 mmHg (systolic blood pressure) and 90 mmHg (diastolic blood pressure) values of ambulatory blood pressure (BP) response using 3 antihypertensive agents of different classes, one of which should be a diuretic in patients fully adherent to antihypertensive therapy. Prevalence of resistant hypertension is ranging from about 5 to 50 % in various cohorts. Initial management requires identification of true treatment resistance by out-of-office BP measurements, assessment of adherence and screening for treatable causes of uncontrolled BP. Recent studies try to indicate possible biomarkers of resistance hypertension. Treatment include lifestyle changes, enhancing treatment adherence and optimization of the doses. An invasive approach to resistant hypertension should be kept for persistently severe cases managed in a specialized hypertension center. This article aims to familiarize readers with the evaluation and management of resistant hypertension by outlining the most recent evidence-based treatment options.
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spelling doaj.art-dec8a7b848b54239952698522d7770f22025-03-02T09:34:19ZrusInterMedserviceЕвразийский Кардиологический Журнал2225-16852305-07482018-09-0103768710.38109/2225-1685-2018-3-76-87300RESISTANT ARTERIAL HYPERTENSIONT. E. Esaulova0A. V. Aksenova1O. A. Sivakova2I. Ye. Chazova3National Medical Research Center of Cardiology of the Ministry of Health of RussiaNational Medical Research Center of Cardiology of the Ministry of Health of RussiaNational Medical Research Center of Cardiology of the Ministry of Health of RussiaNational Medical Research Center of Cardiology of the Ministry of Health of RussiaResistant hypertension is defined as a lack to lower 140 mmHg (systolic blood pressure) and 90 mmHg (diastolic blood pressure) values of ambulatory blood pressure (BP) response using 3 antihypertensive agents of different classes, one of which should be a diuretic in patients fully adherent to antihypertensive therapy. Prevalence of resistant hypertension is ranging from about 5 to 50 % in various cohorts. Initial management requires identification of true treatment resistance by out-of-office BP measurements, assessment of adherence and screening for treatable causes of uncontrolled BP. Recent studies try to indicate possible biomarkers of resistance hypertension. Treatment include lifestyle changes, enhancing treatment adherence and optimization of the doses. An invasive approach to resistant hypertension should be kept for persistently severe cases managed in a specialized hypertension center. This article aims to familiarize readers with the evaluation and management of resistant hypertension by outlining the most recent evidence-based treatment options.https://www.heartj.asia/jour/article/view/301blood pressurearterial hypertensionresistant hypertensiontreatment of resistant hypertensionbiomarkers of resistance hypertensioninvasive approach
spellingShingle T. E. Esaulova
A. V. Aksenova
O. A. Sivakova
I. Ye. Chazova
RESISTANT ARTERIAL HYPERTENSION
Евразийский Кардиологический Журнал
blood pressure
arterial hypertension
resistant hypertension
treatment of resistant hypertension
biomarkers of resistance hypertension
invasive approach
title RESISTANT ARTERIAL HYPERTENSION
title_full RESISTANT ARTERIAL HYPERTENSION
title_fullStr RESISTANT ARTERIAL HYPERTENSION
title_full_unstemmed RESISTANT ARTERIAL HYPERTENSION
title_short RESISTANT ARTERIAL HYPERTENSION
title_sort resistant arterial hypertension
topic blood pressure
arterial hypertension
resistant hypertension
treatment of resistant hypertension
biomarkers of resistance hypertension
invasive approach
url https://www.heartj.asia/jour/article/view/301
work_keys_str_mv AT teesaulova resistantarterialhypertension
AT avaksenova resistantarterialhypertension
AT oasivakova resistantarterialhypertension
AT iyechazova resistantarterialhypertension