Modern understanding of the pathogenesis of basal cell skin cancer
The incidence of basal cell skin cancer is increasing worldwide. The initiation and progression of basal cell skin cancer is due to the interaction of environmental factors and the patient's genetic characteristics. Aberrant activation of the transmission of the Hedgehog signaling pathway is th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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State Scientific Center of Dermatovenereology and Cosmetology
2021-12-01
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| Series: | Vestnik Dermatologii i Venerologii |
| Subjects: | |
| Online Access: | https://vestnikdv.ru/jour/article/viewFile/1277/pdf |
| _version_ | 1827835789313048576 |
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| author | R. R. Saytburkhanov A. A. Kubanov I. N. Kondrakhina X. I. Plakhova |
| author_facet | R. R. Saytburkhanov A. A. Kubanov I. N. Kondrakhina X. I. Plakhova |
| author_sort | R. R. Saytburkhanov |
| collection | DOAJ |
| description | The incidence of basal cell skin cancer is increasing worldwide. The initiation and progression of basal cell skin cancer is due to the interaction of environmental factors and the patient's genetic characteristics. Aberrant activation of the transmission of the Hedgehog signaling pathway is the main pathogenetic pathway of carcinogenesis.
Since basal cell skin cancer is manifested by significant variability of morphological structure, aggressiveness and response to treatment, the disclosure of the molecular genetics of pathogenesis will become the basis for developing new approaches and increasing the effectiveness of treatment, as well as overcoming tumor resistance to treatment.
To search for the necessary literature, the PubMed, MedLine, Web of Science and RSCI databases were used. |
| first_indexed | 2024-03-12T06:15:10Z |
| format | Article |
| id | doaj.art-decb8ed8aa5041aaab35cfae907f6f83 |
| institution | Directory Open Access Journal |
| issn | 0042-4609 2313-6294 |
| language | English |
| last_indexed | 2024-03-12T06:15:10Z |
| publishDate | 2021-12-01 |
| publisher | State Scientific Center of Dermatovenereology and Cosmetology |
| record_format | Article |
| series | Vestnik Dermatologii i Venerologii |
| spelling | doaj.art-decb8ed8aa5041aaab35cfae907f6f832023-09-03T02:41:44ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942021-12-01975385110.25208/vdv12771133Modern understanding of the pathogenesis of basal cell skin cancerR. R. Saytburkhanov0https://orcid.org/0000-0001-6132-5632A. A. Kubanov1https://orcid.org/0000-0002-7625-0503I. N. Kondrakhina2https://orcid.org/0000-0003-3662-9954X. I. Plakhova3https://orcid.org/0000-0003-4169-4128State Research Center of Dermatovenereology and CosmetologyState Research Center of Dermatovenereology and CosmetologyState Research Center of Dermatovenereology and CosmetologyState Research Center of Dermatovenereology and CosmetologyThe incidence of basal cell skin cancer is increasing worldwide. The initiation and progression of basal cell skin cancer is due to the interaction of environmental factors and the patient's genetic characteristics. Aberrant activation of the transmission of the Hedgehog signaling pathway is the main pathogenetic pathway of carcinogenesis. Since basal cell skin cancer is manifested by significant variability of morphological structure, aggressiveness and response to treatment, the disclosure of the molecular genetics of pathogenesis will become the basis for developing new approaches and increasing the effectiveness of treatment, as well as overcoming tumor resistance to treatment. To search for the necessary literature, the PubMed, MedLine, Web of Science and RSCI databases were used.https://vestnikdv.ru/jour/article/viewFile/1277/pdfbasal cell carcinomapathomechanismmicrorna |
| spellingShingle | R. R. Saytburkhanov A. A. Kubanov I. N. Kondrakhina X. I. Plakhova Modern understanding of the pathogenesis of basal cell skin cancer Vestnik Dermatologii i Venerologii basal cell carcinoma pathomechanism microrna |
| title | Modern understanding of the pathogenesis of basal cell skin cancer |
| title_full | Modern understanding of the pathogenesis of basal cell skin cancer |
| title_fullStr | Modern understanding of the pathogenesis of basal cell skin cancer |
| title_full_unstemmed | Modern understanding of the pathogenesis of basal cell skin cancer |
| title_short | Modern understanding of the pathogenesis of basal cell skin cancer |
| title_sort | modern understanding of the pathogenesis of basal cell skin cancer |
| topic | basal cell carcinoma pathomechanism microrna |
| url | https://vestnikdv.ru/jour/article/viewFile/1277/pdf |
| work_keys_str_mv | AT rrsaytburkhanov modernunderstandingofthepathogenesisofbasalcellskincancer AT aakubanov modernunderstandingofthepathogenesisofbasalcellskincancer AT inkondrakhina modernunderstandingofthepathogenesisofbasalcellskincancer AT xiplakhova modernunderstandingofthepathogenesisofbasalcellskincancer |