Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway

Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway

Abstract Background Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful therapeutic agents. Methods The anti-proli...

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Bibliographic Details
Main Authors: Nana Xu, Mengmeng Lu, Jiaxin Wang, Yujia Li, Xiaotian Yang, Xiajie Wei, Jiaoyang Si, Jingru Han, Xiaojuan Yao, Juanmei Zhang, Junqi Liu, Yanming Li, Hushan Yang, Dengke Bao
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Cancer
Subjects:
ESCC
Ivermectin
Apoptosis
Mitochondrial
NF-κB
Online Access:https://doi.org/10.1186/s12885-021-09021-x

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