Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies
Recently, graphene-based nanocomposites are increasingly becoming popular for a variety of biological applications, due to their extraordinary physicochemical properties. Herein, we present an eco-friendly method for the preparation of a novel nanocomposite based on reduced graphene oxide (rGO) deco...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Journal of Saudi Chemical Society |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S131961032300114X |
| _version_ | 1797676321306836992 |
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| author | Alisha Tahir Faroha Liaqat Muhammad Saleem Mohammed Rafi Shaik Syed Farooq Adil Mohammed Rafiq H. Siddiqui Mujeeb Khan |
| author_facet | Alisha Tahir Faroha Liaqat Muhammad Saleem Mohammed Rafi Shaik Syed Farooq Adil Mohammed Rafiq H. Siddiqui Mujeeb Khan |
| author_sort | Alisha Tahir |
| collection | DOAJ |
| description | Recently, graphene-based nanocomposites are increasingly becoming popular for a variety of biological applications, due to their extraordinary physicochemical properties. Herein, we present an eco-friendly method for the preparation of a novel nanocomposite based on reduced graphene oxide (rGO) decorated with tin oxide (SnO2) and zinc oxide (ZnO) nanoparticles. The rGO and binary metal oxides-based nanocomposite (rGO/ZnO/SnO2) with enhanced biocompatibility was prepared by using Mentha longifolia extract as a non-hazardous reducing agent. The rich polyphenolic and flavonoids contents of Mentha longifolia have functioned as potential bio-reductants, which are not only suitable for the synthesis of rGO/ZnO/SnO2, but also effectively stabilized the resulting composite. Initially, to determine the reducing ability of Mentha longifolia, the redox potential and chemical composition of green extract was investigated by cyclic voltammetry (CV) and liquid chromatography-mass spectrometry (LC-MS), respectively. On the other hand, the structural composition and morphology of the resultant composite was confirmed by X-ray diffraction (XRD), Raman spectroscopy, Fourier transform infrared spectroscopy (FT-IR) and UV–visible spectroscopy (UV), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDS). Furthermore, the biological potential of rGO/ZnO/SnO2 is determined by evaluating the antimicrobial and antifungal properties of the resulting composite against various pathogens such as, Staphylococcus aureus (SA), Candida albicans (CA) and Clostridium dificile (CD). Notably, the composite has demonstrated superior antibacterial and antifungal properties when compared to its individual counterparts including rGO, SnO2 and ZnO. Density functional calculations complement the experimental findings, as the periodic boundary conditions reveal high binding energy of −14.8 keV for the rGO/ZnO/SnO2 nanocomposite. |
| first_indexed | 2024-03-11T22:27:18Z |
| format | Article |
| id | doaj.art-ded086a2b38e49a3873ff6eee068a08f |
| institution | Directory Open Access Journal |
| issn | 1319-6103 |
| language | English |
| last_indexed | 2024-03-11T22:27:18Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Saudi Chemical Society |
| spelling | doaj.art-ded086a2b38e49a3873ff6eee068a08f2023-09-24T05:14:27ZengElsevierJournal of Saudi Chemical Society1319-61032023-09-01275101710Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studiesAlisha Tahir0Faroha Liaqat1Muhammad Saleem2Mohammed Rafi Shaik3Syed Farooq Adil4Mohammed Rafiq H. Siddiqui5Mujeeb Khan6Department of Chemistry, Quaid-i-Azam University, 45320, Islamabad, PakistanDepartment of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan; Corresponding authors.National Institute of Lasers and Optronics College, Pakistan Institute of Engineering & Applied Sciences, Nilore, Islamabad, 45650, PakistanDepartment of Chemistry, College of Science, King Saud University, P.O. 2455, Riyadh 11451, Saudi ArabiaDepartment of Chemistry, College of Science, King Saud University, P.O. 2455, Riyadh 11451, Saudi ArabiaDepartment of Chemistry, University of Liverpool, Liverpool L69 7ZD, United KingdomDepartment of Chemistry, College of Science, King Saud University, P.O. 2455, Riyadh 11451, Saudi Arabia; Corresponding authors.Recently, graphene-based nanocomposites are increasingly becoming popular for a variety of biological applications, due to their extraordinary physicochemical properties. Herein, we present an eco-friendly method for the preparation of a novel nanocomposite based on reduced graphene oxide (rGO) decorated with tin oxide (SnO2) and zinc oxide (ZnO) nanoparticles. The rGO and binary metal oxides-based nanocomposite (rGO/ZnO/SnO2) with enhanced biocompatibility was prepared by using Mentha longifolia extract as a non-hazardous reducing agent. The rich polyphenolic and flavonoids contents of Mentha longifolia have functioned as potential bio-reductants, which are not only suitable for the synthesis of rGO/ZnO/SnO2, but also effectively stabilized the resulting composite. Initially, to determine the reducing ability of Mentha longifolia, the redox potential and chemical composition of green extract was investigated by cyclic voltammetry (CV) and liquid chromatography-mass spectrometry (LC-MS), respectively. On the other hand, the structural composition and morphology of the resultant composite was confirmed by X-ray diffraction (XRD), Raman spectroscopy, Fourier transform infrared spectroscopy (FT-IR) and UV–visible spectroscopy (UV), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDS). Furthermore, the biological potential of rGO/ZnO/SnO2 is determined by evaluating the antimicrobial and antifungal properties of the resulting composite against various pathogens such as, Staphylococcus aureus (SA), Candida albicans (CA) and Clostridium dificile (CD). Notably, the composite has demonstrated superior antibacterial and antifungal properties when compared to its individual counterparts including rGO, SnO2 and ZnO. Density functional calculations complement the experimental findings, as the periodic boundary conditions reveal high binding energy of −14.8 keV for the rGO/ZnO/SnO2 nanocomposite.http://www.sciencedirect.com/science/article/pii/S131961032300114XGraphene based nanocompositesQuantum EspressoAntimicrobial activityAnti-fungal activityGreen synthesis |
| spellingShingle | Alisha Tahir Faroha Liaqat Muhammad Saleem Mohammed Rafi Shaik Syed Farooq Adil Mohammed Rafiq H. Siddiqui Mujeeb Khan Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies Journal of Saudi Chemical Society Graphene based nanocomposites Quantum Espresso Antimicrobial activity Anti-fungal activity Green synthesis |
| title | Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies |
| title_full | Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies |
| title_fullStr | Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies |
| title_full_unstemmed | Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies |
| title_short | Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies |
| title_sort | eco friendly synthesis of anti microbial and anti fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies |
| topic | Graphene based nanocomposites Quantum Espresso Antimicrobial activity Anti-fungal activity Green synthesis |
| url | http://www.sciencedirect.com/science/article/pii/S131961032300114X |
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