Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis

Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis

Alternative splicing (AS) and alternative promoter (AP) usage expand the repertories of mammalian transcriptome profiles and thus diversify gene functions. However, our knowledge about the extent and functions of AS and AP usage in mouse early embryogenesis remains elusive. Here, by performing whole...

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Bibliographic Details
Main Authors: Xukun Lu, Zhen-Ao Zhao, Xiaoqing Wang, Xiaoxin Zhang, Yanhua Zhai, Wenbo Deng, Zhaohong Yi, Lei Li
Format: Article
Language:English
Published: The Company of Biologists 2018-03-01
Series:Biology Open
Subjects:
Alternative promoter
Alternative splicing
Germ layer specification
Gastrulation
Mouse embryogenesis
Online Access:http://bio.biologists.org/content/7/3/bio032508

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