The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain
Introduction: Action of the ascending reticular activating system (ARAS) on the cerebral cortex is responsible for achievement of consciousness. In this study, we attempted to reconstruct the lower single component of the ARAS from the reticular formation (RF) to the thalamus in the normal human bra...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-07-01
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| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2013.00416/full |
| _version_ | 1798044205559316480 |
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| author | Sang Seok eYeo Pyung Hun eChang Sung Ho eJang |
| author_facet | Sang Seok eYeo Pyung Hun eChang Sung Ho eJang |
| author_sort | Sang Seok eYeo |
| collection | DOAJ |
| description | Introduction: Action of the ascending reticular activating system (ARAS) on the cerebral cortex is responsible for achievement of consciousness. In this study, we attempted to reconstruct the lower single component of the ARAS from the reticular formation (RF) to the thalamus in the normal human brain using diffusion tensor imaging (DTI).Methods: Twenty six normal healthy subjects were recruited for this study. A 1.5-T scanner was used for scanning of diffusion tensor images, and the lower single component of the ARAS was reconstructed using FMRIB software. We utilized two ROIs for reconstruction of the lower single component of the ARAS: the seed ROI - the RF of the pons at the level of the trigeminal nerve entry zone, the target ROI - the intralaminar nuclei of the thalamus at the level of the commissural plane.Results: The reconstructed ARAS originated from the pontine RF, ascended through the mesencephalic tegmentum just posterior to the red nucleus, and then terminated on the intralaminar nuclei of the thalamus. No significant differences in fractional anisotropy, mean diffusivity, and tract number were observed between hemispheres (P>0.05)Conclusion: We reconstructed the lower single component of the ARAS from the RF to the thalamus in the human brain using DTI. The results of this study might be of value for the diagnosis and prognosis of patients with impaired consciousness |
| first_indexed | 2024-04-11T22:59:55Z |
| format | Article |
| id | doaj.art-ded0f9fc61194345b72c7f89b2997c41 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-04-11T22:59:55Z |
| publishDate | 2013-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-ded0f9fc61194345b72c7f89b2997c412022-12-22T03:58:13ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612013-07-01710.3389/fnhum.2013.0041654828The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human BrainSang Seok eYeo0Pyung Hun eChang1Sung Ho eJang2Yeungnam universityDaegu Gyeongbuk Institute of Science & TechnologyYeungnam universityIntroduction: Action of the ascending reticular activating system (ARAS) on the cerebral cortex is responsible for achievement of consciousness. In this study, we attempted to reconstruct the lower single component of the ARAS from the reticular formation (RF) to the thalamus in the normal human brain using diffusion tensor imaging (DTI).Methods: Twenty six normal healthy subjects were recruited for this study. A 1.5-T scanner was used for scanning of diffusion tensor images, and the lower single component of the ARAS was reconstructed using FMRIB software. We utilized two ROIs for reconstruction of the lower single component of the ARAS: the seed ROI - the RF of the pons at the level of the trigeminal nerve entry zone, the target ROI - the intralaminar nuclei of the thalamus at the level of the commissural plane.Results: The reconstructed ARAS originated from the pontine RF, ascended through the mesencephalic tegmentum just posterior to the red nucleus, and then terminated on the intralaminar nuclei of the thalamus. No significant differences in fractional anisotropy, mean diffusivity, and tract number were observed between hemispheres (P>0.05)Conclusion: We reconstructed the lower single component of the ARAS from the RF to the thalamus in the human brain using DTI. The results of this study might be of value for the diagnosis and prognosis of patients with impaired consciousnesshttp://journal.frontiersin.org/Journal/10.3389/fnhum.2013.00416/fullConsciousnessDiffusion Tensor ImagingReticular Formationbrainstemascending reticular activating systemb |
| spellingShingle | Sang Seok eYeo Pyung Hun eChang Sung Ho eJang The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain Frontiers in Human Neuroscience Consciousness Diffusion Tensor Imaging Reticular Formation brainstem ascending reticular activating system b |
| title | The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain |
| title_full | The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain |
| title_fullStr | The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain |
| title_full_unstemmed | The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain |
| title_short | The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain |
| title_sort | ascending reticular activating system from pontine reticular formation to the thalamus in the human brain |
| topic | Consciousness Diffusion Tensor Imaging Reticular Formation brainstem ascending reticular activating system b |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2013.00416/full |
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