Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation)
In the article a case of non-resectable differentiated thyroid cancer (DTC) is described. A recurrent thyroid tumor deforms the oropharyngeal lumen and laryngeal vestibule and bears down on the left esophageal wall and trachea. The authors present literature data on Nexavar target therapy and focus...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2017-04-01
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| Series: | Опухоли головы и шеи |
| Subjects: | |
| Online Access: | https://ogsh.abvpress.ru/jour/article/view/242 |
| _version_ | 1826558243865886720 |
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| author | P. A. Isaev S. V. Vasilkov I. S. Pimonova F. E. Sevrukov V. V. Polkin D. Yu. Syomin A. A. Ilyin V. S. Medvedev N. K. Silantyeva T. A. Agababyan |
| author_facet | P. A. Isaev S. V. Vasilkov I. S. Pimonova F. E. Sevrukov V. V. Polkin D. Yu. Syomin A. A. Ilyin V. S. Medvedev N. K. Silantyeva T. A. Agababyan |
| author_sort | P. A. Isaev |
| collection | DOAJ |
| description | In the article a case of non-resectable differentiated thyroid cancer (DTC) is described. A recurrent thyroid tumor deforms the oropharyngeal lumen and laryngeal vestibule and bears down on the left esophageal wall and trachea. The authors present literature data on Nexavar target therapy and focus on the fact that no cases of combination treatment with target therapy and surgery of non-resectable progressive DTC were described until now. In view of this, this clinical report is unique and dictates a need to determine new Nexavar (Sorafenib) indications for use in a neoadjuvant regimen. |
| first_indexed | 2024-04-10T01:59:10Z |
| format | Article |
| id | doaj.art-ded1cfa906454b0aa1a96f22743f75fb |
| institution | Directory Open Access Journal |
| issn | 2222-1468 2411-4634 |
| language | Russian |
| last_indexed | 2025-03-14T08:41:24Z |
| publishDate | 2017-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли головы и шеи |
| spelling | doaj.art-ded1cfa906454b0aa1a96f22743f75fb2025-03-02T12:53:48ZrusABV-pressОпухоли головы и шеи2222-14682411-46342017-04-0171869010.17650/2222-1468-2017-7-1-86-90227Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation)P. A. Isaev0S. V. Vasilkov1I. S. Pimonova2F. E. Sevrukov3V. V. Polkin4D. Yu. Syomin5A. A. Ilyin6V. S. Medvedev7N. K. Silantyeva8T. A. Agababyan9A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of RussiaIn the article a case of non-resectable differentiated thyroid cancer (DTC) is described. A recurrent thyroid tumor deforms the oropharyngeal lumen and laryngeal vestibule and bears down on the left esophageal wall and trachea. The authors present literature data on Nexavar target therapy and focus on the fact that no cases of combination treatment with target therapy and surgery of non-resectable progressive DTC were described until now. In view of this, this clinical report is unique and dictates a need to determine new Nexavar (Sorafenib) indications for use in a neoadjuvant regimen.https://ogsh.abvpress.ru/jour/article/view/242radioiodine-resistant thyroid cancertarget therapynexavar |
| spellingShingle | P. A. Isaev S. V. Vasilkov I. S. Pimonova F. E. Sevrukov V. V. Polkin D. Yu. Syomin A. A. Ilyin V. S. Medvedev N. K. Silantyeva T. A. Agababyan Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation) Опухоли головы и шеи radioiodine-resistant thyroid cancer target therapy nexavar |
| title | Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation) |
| title_full | Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation) |
| title_fullStr | Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation) |
| title_full_unstemmed | Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation) |
| title_short | Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation) |
| title_sort | neoadjuvant target therapy of differentiated thyroid cancer clinical observation |
| topic | radioiodine-resistant thyroid cancer target therapy nexavar |
| url | https://ogsh.abvpress.ru/jour/article/view/242 |
| work_keys_str_mv | AT paisaev neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT svvasilkov neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT ispimonova neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT fesevrukov neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT vvpolkin neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT dyusyomin neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT aailyin neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT vsmedvedev neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT nksilantyeva neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation AT taagababyan neoadjuvanttargettherapyofdifferentiatedthyroidcancerclinicalobservation |