FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size
Aging is a multifactorial process that is characterized by decline in muscle mass and performance. Several factors, including reduced exercise, poor nutrition and modified hormonal metabolism, are responsible for changes in the rates of protein synthesis and degradation that drive skeletal muscle ma...
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2012-03-01
|
| Series: | European Journal of Translational Myology |
| Subjects: | |
| Online Access: | http://pagepressjournals.org/index.php/bam/article/view/1794 |
| _version_ | 1818621563356839936 |
|---|---|
| author | Helmut Kern Stefan Loefler Christian Hofer Michael Vogelauer Samantha Burggraf Martina Grim-Stieger Jan Cvecka Dusan Hamar Nejc Sarabon Feliciano Protasi Antonio Musarò Marco Sandri Katia Rossini Ugo Carraro Sandra Zampieri |
| author_facet | Helmut Kern Stefan Loefler Christian Hofer Michael Vogelauer Samantha Burggraf Martina Grim-Stieger Jan Cvecka Dusan Hamar Nejc Sarabon Feliciano Protasi Antonio Musarò Marco Sandri Katia Rossini Ugo Carraro Sandra Zampieri |
| author_sort | Helmut Kern |
| collection | DOAJ |
| description | Aging is a multifactorial process that is characterized by decline in muscle mass and performance. Several factors, including reduced exercise, poor nutrition and modified hormonal metabolism, are responsible for changes in the rates of protein synthesis and degradation that drive skeletal muscle mass reduction with a consequent decline of force generation and mobility functional performances. Seniors with normal life style were enrolled: two groups in Vienna (n=32) and two groups in Bratislava: (n=19). All subjects were healthy and declared not to have any specific physical/disease problems. The two Vienna groups of seniors exercised for 10 weeks with two different types of training (leg press at the hospital or home-based functional electrical stimulation, h-b FES). Demografic data (age, height and weight) were recorded before and after the training period and before and after the training period the patients were submitted to mobility functional analyses and muscle biopsies. The mobility functional analyses were: 1. gait speed (10m test fastest speed, in m/s); 2. time which the subject needed to rise from a chair for five times (5x Chair-Rise, in s); 3. Timed –Up-Go- Test, in s; 4. Stair-Test, in s; 5. isometric measurement of quadriceps force (Torque/kg, in Nm/kg); and 6. Dynamic Balance in mm. Preliminary analyses of muscle biopsies from quadriceps in some of the Vienna and Bratislava patients present morphometric results consistent with their functional behaviors. The statistically significant improvements in functional testings here reported demonstrates the effectiveness of h-b FES, and strongly support h-b FES, as a safe home-based method to improve contractility and performances of ageing muscles. |
| first_indexed | 2024-12-16T18:11:16Z |
| format | Article |
| id | doaj.art-ded246c86e3343adb7cfaf9a61d11b8f |
| institution | Directory Open Access Journal |
| issn | 2037-7452 2037-7460 |
| language | English |
| last_indexed | 2024-12-16T18:11:16Z |
| publishDate | 2012-03-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | European Journal of Translational Myology |
| spelling | doaj.art-ded246c86e3343adb7cfaf9a61d11b8f2022-12-21T22:21:47ZengPAGEPress PublicationsEuropean Journal of Translational Myology2037-74522037-74602012-03-01221-2616710.4081/ejtm.2012.17941169FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber sizeHelmut Kern0Stefan Loefler1Christian Hofer2Michael Vogelauer3Samantha Burggraf4Martina Grim-Stieger5Jan Cvecka6Dusan Hamar7Nejc Sarabon8Feliciano Protasi9Antonio Musarò10Marco Sandri11Katia Rossini12Ugo Carraro13Sandra Zampieri14Dept. of Physical Medicine and Rehabilitation, Wilhelminenspital WienLudwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, WienLudwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, WienDept. of Physical Medicine and Rehabilitation, Wilhelminenspital WienLudwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, WienDept. of Physical Medicine and Rehabilitation, Wilhelminenspital WienFaculty of Physical Education and Sport, Comenius University, BratislavaFaculty of Physical Education and Sport, Comenius University, BratislavaUniversity of Primorska, Science and Research Centre, Institute for Kinesiological Research, KoperCeSI - Center for Research on Ageing & DNI – Dept. Neuroscience and Imaging, University G. d'Annunzio of ChietiDAHFMO-Unit of Histology and Medical Embryology, IIM, Sapienza University of RomeVenetian Institute of Molecular Medicine, Dulbecco Telethon Institute, and Dept. of Biomedical Science, University of PadovaLaboratory of Translational Myology, Dept. Biomedical Sciences, University of PadovaLaboratory of Translational Myology, Dept. Biomedical Sciences, University of PadovaLaboratory of Translational Myology, Dept. Biomedical Sciences, University of PadovaAging is a multifactorial process that is characterized by decline in muscle mass and performance. Several factors, including reduced exercise, poor nutrition and modified hormonal metabolism, are responsible for changes in the rates of protein synthesis and degradation that drive skeletal muscle mass reduction with a consequent decline of force generation and mobility functional performances. Seniors with normal life style were enrolled: two groups in Vienna (n=32) and two groups in Bratislava: (n=19). All subjects were healthy and declared not to have any specific physical/disease problems. The two Vienna groups of seniors exercised for 10 weeks with two different types of training (leg press at the hospital or home-based functional electrical stimulation, h-b FES). Demografic data (age, height and weight) were recorded before and after the training period and before and after the training period the patients were submitted to mobility functional analyses and muscle biopsies. The mobility functional analyses were: 1. gait speed (10m test fastest speed, in m/s); 2. time which the subject needed to rise from a chair for five times (5x Chair-Rise, in s); 3. Timed –Up-Go- Test, in s; 4. Stair-Test, in s; 5. isometric measurement of quadriceps force (Torque/kg, in Nm/kg); and 6. Dynamic Balance in mm. Preliminary analyses of muscle biopsies from quadriceps in some of the Vienna and Bratislava patients present morphometric results consistent with their functional behaviors. The statistically significant improvements in functional testings here reported demonstrates the effectiveness of h-b FES, and strongly support h-b FES, as a safe home-based method to improve contractility and performances of ageing muscles.http://pagepressjournals.org/index.php/bam/article/view/1794FES, exercise training, aging, functional analyses, mobility, muscle fiber size |
| spellingShingle | Helmut Kern Stefan Loefler Christian Hofer Michael Vogelauer Samantha Burggraf Martina Grim-Stieger Jan Cvecka Dusan Hamar Nejc Sarabon Feliciano Protasi Antonio Musarò Marco Sandri Katia Rossini Ugo Carraro Sandra Zampieri FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size European Journal of Translational Myology FES, exercise training, aging, functional analyses, mobility, muscle fiber size |
| title | FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size |
| title_full | FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size |
| title_fullStr | FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size |
| title_full_unstemmed | FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size |
| title_short | FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size |
| title_sort | fes training in aging interim results show statistically significant improvements in mobility and muscle fiber size |
| topic | FES, exercise training, aging, functional analyses, mobility, muscle fiber size |
| url | http://pagepressjournals.org/index.php/bam/article/view/1794 |
| work_keys_str_mv | AT helmutkern festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT stefanloefler festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT christianhofer festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT michaelvogelauer festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT samanthaburggraf festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT martinagrimstieger festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT jancvecka festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT dusanhamar festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT nejcsarabon festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT felicianoprotasi festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT antoniomusaro festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT marcosandri festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT katiarossini festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT ugocarraro festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize AT sandrazampieri festraininginaginginterimresultsshowstatisticallysignificantimprovementsinmobilityandmusclefibersize |