Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjects
Abstract Introduction The motor‐related bioelectric brain activity of healthy young and old subjects was studied to understand the effect of aging on motor execution. A visually cued finger tapping movement paradigm and high‐density EEG were used to examine the time and frequency characteristics. Me...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-08-01
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| Series: | Brain and Behavior |
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| Online Access: | https://doi.org/10.1002/brb3.3176 |
| _version_ | 1797359518409031680 |
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| author | Adam Gyulai Janos Körmendi Mohamed F. Issa Zoltan Juhasz Zoltan Nagy |
| author_facet | Adam Gyulai Janos Körmendi Mohamed F. Issa Zoltan Juhasz Zoltan Nagy |
| author_sort | Adam Gyulai |
| collection | DOAJ |
| description | Abstract Introduction The motor‐related bioelectric brain activity of healthy young and old subjects was studied to understand the effect of aging on motor execution. A visually cued finger tapping movement paradigm and high‐density EEG were used to examine the time and frequency characteristics. Methods Twenty‐two young and 22 healthy elderly adults participated in the study. Repeated trials of left and right index finger movements were recorded with a 128‐channel EEG. Event‐Related Spectral Perturbation (ERSP), Inter Trial Coherence (ITC), and Functional Connectivity were computed and compared between the age groups. Results An age‐dependent theta and alpha band ERSP decrease was observed over the frontal–midline area. Decrease of beta band ERSP was found over the ipsilateral central–parietal regions. Significant ITC differences were found in the delta and theta bands between old and young subjects over the contralateral parietal–occipital areas. The spatial extent of increased ITC values was larger in old subjects. The movement execution of older subjects showed higher global efficiency in the delta and theta bands, and higher local efficiency and node strengths in the delta, theta, alpha, and beta bands. Conclusion As functional compensation of aging, elderly motor networks involve more nonmotor, parietal–occipital, and frontal areas, with higher global and local efficiency, node strength. ERSP and ITC changes seem to be sensitive and complementary biomarkers of age‐related motor execution. |
| first_indexed | 2024-03-08T15:25:00Z |
| format | Article |
| id | doaj.art-ded2a9f6270e4de6ad07e46b23199090 |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-03-08T15:25:00Z |
| publishDate | 2023-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-ded2a9f6270e4de6ad07e46b231990902024-01-10T10:25:35ZengWileyBrain and Behavior2162-32792023-08-01138n/an/a10.1002/brb3.3176Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjectsAdam Gyulai0Janos Körmendi1Mohamed F. Issa2Zoltan Juhasz3Zoltan Nagy4Szentagothai Doctoral School Semmelweis University BudapestHungaryLaboratory of Bioelectric Brain ImagingNational Mental, Neurological and Neurosurgical InstituteBudapestHungaryDepartment of Electrical Engineering and Information Systems University of Pannonia VeszpremHungaryDepartment of Electrical Engineering and Information Systems University of Pannonia VeszpremHungaryLaboratory of Bioelectric Brain ImagingNational Mental, Neurological and Neurosurgical InstituteBudapestHungaryAbstract Introduction The motor‐related bioelectric brain activity of healthy young and old subjects was studied to understand the effect of aging on motor execution. A visually cued finger tapping movement paradigm and high‐density EEG were used to examine the time and frequency characteristics. Methods Twenty‐two young and 22 healthy elderly adults participated in the study. Repeated trials of left and right index finger movements were recorded with a 128‐channel EEG. Event‐Related Spectral Perturbation (ERSP), Inter Trial Coherence (ITC), and Functional Connectivity were computed and compared between the age groups. Results An age‐dependent theta and alpha band ERSP decrease was observed over the frontal–midline area. Decrease of beta band ERSP was found over the ipsilateral central–parietal regions. Significant ITC differences were found in the delta and theta bands between old and young subjects over the contralateral parietal–occipital areas. The spatial extent of increased ITC values was larger in old subjects. The movement execution of older subjects showed higher global efficiency in the delta and theta bands, and higher local efficiency and node strengths in the delta, theta, alpha, and beta bands. Conclusion As functional compensation of aging, elderly motor networks involve more nonmotor, parietal–occipital, and frontal areas, with higher global and local efficiency, node strength. ERSP and ITC changes seem to be sensitive and complementary biomarkers of age‐related motor execution.https://doi.org/10.1002/brb3.3176agingEEGEvent‐Related Spectral PerturbationFunctional ConnectivityInter Trial Coherencemotor execution |
| spellingShingle | Adam Gyulai Janos Körmendi Mohamed F. Issa Zoltan Juhasz Zoltan Nagy Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjects Brain and Behavior aging EEG Event‐Related Spectral Perturbation Functional Connectivity Inter Trial Coherence motor execution |
| title | Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjects |
| title_full | Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjects |
| title_fullStr | Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjects |
| title_full_unstemmed | Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjects |
| title_short | Event‐Related Spectral Perturbation, Inter Trial Coherence, and Functional Connectivity in motor execution: A comparative EEG study of old and young subjects |
| title_sort | event related spectral perturbation inter trial coherence and functional connectivity in motor execution a comparative eeg study of old and young subjects |
| topic | aging EEG Event‐Related Spectral Perturbation Functional Connectivity Inter Trial Coherence motor execution |
| url | https://doi.org/10.1002/brb3.3176 |
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