Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With Pneumonia
Background: Pneumonia is a major cause of childhood morbidity and mortality worldwide. It can be complicated by bacteremia. Congenital heart diseases (CHD) that cause increased pulmonary blood flow are a common predisposing factor for pneumonia in children. Aim of the Work: We aimed to identify if...
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| Format: | Article |
| Language: | English |
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Cairo University, Faculty of Medicine, Department of Pediatrics
2021-07-01
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| Series: | Pediatric Sciences Journal |
| Subjects: | |
| Online Access: | https://cupsj.journals.ekb.eg/article_179784_aa690fe02b16c0271d689b46c3ba965b.pdf |
| _version_ | 1797791626434707456 |
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| author | Azza K. Abdelmegeid Sara S. Ragab Fatma Al Zahraa Mostafa Mai A. Hassan Hala A. ElGindy |
| author_facet | Azza K. Abdelmegeid Sara S. Ragab Fatma Al Zahraa Mostafa Mai A. Hassan Hala A. ElGindy |
| author_sort | Azza K. Abdelmegeid |
| collection | DOAJ |
| description | Background: Pneumonia is a major cause of childhood morbidity and mortality worldwide. It can be complicated by bacteremia. Congenital heart diseases (CHD) that cause increased pulmonary blood flow are a common predisposing factor for pneumonia in children.
Aim of the Work: We aimed to identify if children with pneumonia suffer from bacteremia and to identify the most common organisms causing bacteremia in cases of pneumonia with and without congenital heart disease and to study role of CHD in influencing type of bacteremia in pneumonia.
Patients and Methods: We conducted a pilot prospective study at Pediatric Hospital, Cairo University on 55 children with pneumonia (group 1) and 55 children with pneumonia and CHD (group 2). They all underwent complete blood counts, blood cultures and chest x-ray.
Results: The frequency of bacteremia was 56.4% in children with pneumonia and no CHD and 38.2% in those with pneumonia and CHD. In group with pneumonia and no CHD blood culture results showed no growth in 24 cases (43.6%), Klebsiella spp. growth 11 cases (20%), Coagulase negative staphylococci (CONS) in 6 cases (10.9%), Methicillin Resistant Staphylococcus aureus in 4 cases (7.3%), Candida albicans in 2 cases (3.6%) and Pseudomonas spp. in 2 cases (3.6%). While the blood cultures in the group with pneumonia and CHD showed no growth in 34 cases (61.8%), Klebsiella spp. in 10 cases (18.2%), CONS in 5 cases (9.1%) and Candida albicans in 3 cases (5.5%) and no statistically significant difference was found.
Conclusion: Frequency of bacteremia in children with pneumonia with and without congenital heart disease were not significantly different, the most common organism causing bacteremia in cases of pneumonia with or without congenital heart disease is Klebsiella spp < em>. and the most sensitive antibiotic is polymyxin. |
| first_indexed | 2024-03-13T02:21:28Z |
| format | Article |
| id | doaj.art-ded7726cff754989ab9d97388c5ed6ce |
| institution | Directory Open Access Journal |
| issn | 2805-279X 2682-3985 |
| language | English |
| last_indexed | 2024-03-13T02:21:28Z |
| publishDate | 2021-07-01 |
| publisher | Cairo University, Faculty of Medicine, Department of Pediatrics |
| record_format | Article |
| series | Pediatric Sciences Journal |
| spelling | doaj.art-ded7726cff754989ab9d97388c5ed6ce2023-06-30T09:39:19ZengCairo University, Faculty of Medicine, Department of PediatricsPediatric Sciences Journal2805-279X2682-39852021-07-0112717610.21608/CUPSJ.2021.77422.1020Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With PneumoniaAzza K. Abdelmegeid0https://orcid.org/0000-0002-6665-3771Sara S. Ragab1Fatma Al Zahraa Mostafa2https://orcid.org/0000-0002-9624-2375Mai A. Hassan3Hala A. ElGindy4Department of Pediatrics, Faculty of Medicine, Cairo University, EgyptDepartment of Pediatrics, Faculty of Medicine, Cairo University, EgyptDepartment of Pediatrics, Faculty of Medicine, Cairo University, EgyptDepartment of Clinical Pathology, Faculty of Medicine, Cairo University, EgyptDepartment of Pediatrics, Faculty of Medicine, Cairo University, EgyptBackground: Pneumonia is a major cause of childhood morbidity and mortality worldwide. It can be complicated by bacteremia. Congenital heart diseases (CHD) that cause increased pulmonary blood flow are a common predisposing factor for pneumonia in children. Aim of the Work: We aimed to identify if children with pneumonia suffer from bacteremia and to identify the most common organisms causing bacteremia in cases of pneumonia with and without congenital heart disease and to study role of CHD in influencing type of bacteremia in pneumonia. Patients and Methods: We conducted a pilot prospective study at Pediatric Hospital, Cairo University on 55 children with pneumonia (group 1) and 55 children with pneumonia and CHD (group 2). They all underwent complete blood counts, blood cultures and chest x-ray. Results: The frequency of bacteremia was 56.4% in children with pneumonia and no CHD and 38.2% in those with pneumonia and CHD. In group with pneumonia and no CHD blood culture results showed no growth in 24 cases (43.6%), Klebsiella spp. growth 11 cases (20%), Coagulase negative staphylococci (CONS) in 6 cases (10.9%), Methicillin Resistant Staphylococcus aureus in 4 cases (7.3%), Candida albicans in 2 cases (3.6%) and Pseudomonas spp. in 2 cases (3.6%). While the blood cultures in the group with pneumonia and CHD showed no growth in 34 cases (61.8%), Klebsiella spp. in 10 cases (18.2%), CONS in 5 cases (9.1%) and Candida albicans in 3 cases (5.5%) and no statistically significant difference was found. Conclusion: Frequency of bacteremia in children with pneumonia with and without congenital heart disease were not significantly different, the most common organism causing bacteremia in cases of pneumonia with or without congenital heart disease is Klebsiella spp < em>. and the most sensitive antibiotic is polymyxin. https://cupsj.journals.ekb.eg/article_179784_aa690fe02b16c0271d689b46c3ba965b.pdfpneumoniacongenital heart diseasebacteremiapediatricchildren |
| spellingShingle | Azza K. Abdelmegeid Sara S. Ragab Fatma Al Zahraa Mostafa Mai A. Hassan Hala A. ElGindy Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With Pneumonia Pediatric Sciences Journal pneumonia congenital heart disease bacteremia pediatric children |
| title | Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With Pneumonia |
| title_full | Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With Pneumonia |
| title_fullStr | Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With Pneumonia |
| title_full_unstemmed | Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With Pneumonia |
| title_short | Congenital Heart Disease Does Not Increase Risk of Bacteremia In Children With Pneumonia |
| title_sort | congenital heart disease does not increase risk of bacteremia in children with pneumonia |
| topic | pneumonia congenital heart disease bacteremia pediatric children |
| url | https://cupsj.journals.ekb.eg/article_179784_aa690fe02b16c0271d689b46c3ba965b.pdf |
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