Injection of a PMMA‐doped MSC spheroid gel for the treatment of painful osteoporotic vertebral compression fractures

Injection of a PMMA‐doped MSC spheroid gel for the treatment of painful osteoporotic vertebral compression fractures

Abstract We aimed to develop a biocompatible treatment to overcome the limitations of polymethyl methacrylate (PMMA) vertebroplasty for osteoporotic compression fracture patients. We synthesized an injectable hydrogel containing PMMA. Mesenchymal stem cell (MSC) spheroids were included in the inject...

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Bibliographic Details
Main Authors: Wan‐Kyu Ko, Daye Lee, Seong Jun Kim, Gong Ho Han, Donghyun Lee, Seung Hun Sheen, Seil Sohn
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Bioengineering & Translational Medicine
Subjects:
mesenchymal stem cell
osteoporotic fracture
pain
PMMA
spheroid
Online Access:https://doi.org/10.1002/btm2.10577

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