ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY.
Background This study aimed to determine the prevalence of Acute Kidney Injury (AKI) and its clinical characteristics and outcomes among pregnant women in the Indian state of Bihar with pre-eclampsia or Hemolysis, Elevated Liver Enzymes, and Low Platelet (HELLP) syndrome. Methods A retrospect...
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| Format: | Article |
| Language: | English |
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Student's Journal of Health Research
2023-06-01
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| Series: | Student's Journal of Health Research Africa |
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| Online Access: | https://sjhresearchafrica.org/index.php/public-html/article/view/461 |
| _version_ | 1827912557286916096 |
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| author | Akanksha Suman Sangeeta Sinha |
| author_facet | Akanksha Suman Sangeeta Sinha |
| author_sort | Akanksha Suman |
| collection | DOAJ |
| description |
Background
This study aimed to determine the prevalence of Acute Kidney Injury (AKI) and its clinical characteristics and outcomes among pregnant women in the Indian state of Bihar with pre-eclampsia or Hemolysis, Elevated Liver Enzymes, and Low Platelet (HELLP) syndrome.
Methods
A retrospective unit study was conducted at tertiary care facilities in Bihar on women diagnosed with pre-eclampsia or HELLP syndrome during pregnancy. All the gathered data, including demographic information, obstetric history, test results, and maternal and foetal outcomes, originated from medical records. A statistical analysis was conducted on the incidence rates of AKI and the associated risk variables.
Results
One hundred pregnant women participated in this study, in which 15% of pregnant participants with pre-eclampsia or HELLP syndrome, suffered with acute kidney damage. Acute kidney damage risk factors include maternal age over 35, first-time pregnancy, severe hypertension, and delayed antihypertensive drug initiation. Acute renal injury caused respiratory distress, pulmonary oedema, and dialysis in mothers. AKI-compromised pregnancies exhibited more significant rates of preterm birth, low birth weight, and perinatal mortality.
Conclusion
Pregnant women in Bihar with pre-eclampsia or HELLP syndrome have a significant rate of AKI. First, identify risk variables and then quickly apply management techniques to avoid and control AKI in this population. Prenatal care, regular blood pressure monitoring, and early antihypertensive treatment are crucial to lowering AKI prevalence and severity.
Recommendation
For improved management of AKI in expectant women with pre-eclampsia or HELLP syndrome, blood pressure and urine protein levels should be routinely monitored as part of prenatal care. Protect against AKI by initiating antihypertensive treatment promptly and promoting interdisciplinary collaboration for the overall management of high-risk pregnancies. Promote research and surveillance to evaluate and improve current AKI preventive measures, and establish long-term follow-up programmes to assess postpartum kidney health.
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| first_indexed | 2024-03-13T02:17:24Z |
| format | Article |
| id | doaj.art-dee7ab197bd14208969a19b8f1899077 |
| institution | Directory Open Access Journal |
| issn | 2709-9997 |
| language | English |
| last_indexed | 2024-03-13T02:17:24Z |
| publishDate | 2023-06-01 |
| publisher | Student's Journal of Health Research |
| record_format | Article |
| series | Student's Journal of Health Research Africa |
| spelling | doaj.art-dee7ab197bd14208969a19b8f18990772023-06-30T11:43:26ZengStudent's Journal of Health ResearchStudent's Journal of Health Research Africa2709-99972023-06-014610.51168/sjhrafrica.v4i6.461ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY.Akanksha Suman0Sangeeta Sinha1Department of Obstetrics and Gynecology, Patna Medical College and Hospital Patna, Bihar.Department of Obstetrics and Gynecology, Patna Medical college and hospital, Patna. Background This study aimed to determine the prevalence of Acute Kidney Injury (AKI) and its clinical characteristics and outcomes among pregnant women in the Indian state of Bihar with pre-eclampsia or Hemolysis, Elevated Liver Enzymes, and Low Platelet (HELLP) syndrome. Methods A retrospective unit study was conducted at tertiary care facilities in Bihar on women diagnosed with pre-eclampsia or HELLP syndrome during pregnancy. All the gathered data, including demographic information, obstetric history, test results, and maternal and foetal outcomes, originated from medical records. A statistical analysis was conducted on the incidence rates of AKI and the associated risk variables. Results One hundred pregnant women participated in this study, in which 15% of pregnant participants with pre-eclampsia or HELLP syndrome, suffered with acute kidney damage. Acute kidney damage risk factors include maternal age over 35, first-time pregnancy, severe hypertension, and delayed antihypertensive drug initiation. Acute renal injury caused respiratory distress, pulmonary oedema, and dialysis in mothers. AKI-compromised pregnancies exhibited more significant rates of preterm birth, low birth weight, and perinatal mortality. Conclusion Pregnant women in Bihar with pre-eclampsia or HELLP syndrome have a significant rate of AKI. First, identify risk variables and then quickly apply management techniques to avoid and control AKI in this population. Prenatal care, regular blood pressure monitoring, and early antihypertensive treatment are crucial to lowering AKI prevalence and severity. Recommendation For improved management of AKI in expectant women with pre-eclampsia or HELLP syndrome, blood pressure and urine protein levels should be routinely monitored as part of prenatal care. Protect against AKI by initiating antihypertensive treatment promptly and promoting interdisciplinary collaboration for the overall management of high-risk pregnancies. Promote research and surveillance to evaluate and improve current AKI preventive measures, and establish long-term follow-up programmes to assess postpartum kidney health. https://sjhresearchafrica.org/index.php/public-html/article/view/461Acute kidney injuryBiharHELLP syndromePre-eclampsiaPregnancy |
| spellingShingle | Akanksha Suman Sangeeta Sinha ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY. Student's Journal of Health Research Africa Acute kidney injury Bihar HELLP syndrome Pre-eclampsia Pregnancy |
| title | ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY. |
| title_full | ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY. |
| title_fullStr | ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY. |
| title_full_unstemmed | ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY. |
| title_short | ACUTE KIDNEY INJURY IN PREGNANCIES COMPLICATED WITH PRE-ECLAMPSIA OR HELLP SYNDROME: A RETROSPECTIVE STUDY. |
| title_sort | acute kidney injury in pregnancies complicated with pre eclampsia or hellp syndrome a retrospective study |
| topic | Acute kidney injury Bihar HELLP syndrome Pre-eclampsia Pregnancy |
| url | https://sjhresearchafrica.org/index.php/public-html/article/view/461 |
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