Molecular Modeling of Viral Type I Fusion Proteins: Inhibitors of Influenza Virus Hemagglutinin and the Spike Protein of Coronavirus

Molecular Modeling of Viral Type I Fusion Proteins: Inhibitors of Influenza Virus Hemagglutinin and the Spike Protein of Coronavirus

The fusion of viral and cell membranes is one of the basic processes in the life cycles of viruses. A number of enveloped viruses confer fusion of the viral envelope and the cell membrane using surface viral fusion proteins. Their conformational rearrangements lead to the unification of lipid bilaye...

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Bibliographic Details
Main Authors: Sophia S. Borisevich, Vladimir V. Zarubaev, Dmitriy N. Shcherbakov, Olga I. Yarovaya, Nariman F. Salakhutdinov
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Viruses
Subjects:
viral fusion proteins type I
influenza virus
hemagglutinin
coronavirus
S-protein
SARS-CoV-2
Online Access:https://www.mdpi.com/1999-4915/15/4/902

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