A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection

A new dissolved oxygen sensor based on optical fiber surface plasmon resonance (SPR) theory and the mechanism of oxygen transporting by hemoglobin was proposed and demonstrated. Gold film was coated on the surface of the optical fiber sensing area, and hemoglobin was modified on the surface of the g...

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Main Authors: Meiju Luo, Qi Wang
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Alexandria Engineering Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110016820306852
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author Meiju Luo
Qi Wang
author_facet Meiju Luo
Qi Wang
author_sort Meiju Luo
collection DOAJ
description A new dissolved oxygen sensor based on optical fiber surface plasmon resonance (SPR) theory and the mechanism of oxygen transporting by hemoglobin was proposed and demonstrated. Gold film was coated on the surface of the optical fiber sensing area, and hemoglobin was modified on the surface of the gold film. The experimental results show that the sensor has good linearity and the limit of detection (LOD) of the sensor is 0.03 mg/L. In addition, in order to enhance the sensitivity of the sensor, the carbon nanotubes were modified on the surface of the gold film of the fiber, and then the hemoglobin was modified in the outermost layer. Through experiments, it was found that the sensitivity of the sensor which modified with carbon nanotubes is 2.8-folds higher than that only modified hemoglobin, the linearity is better, and the LOD is reduced to 0.01 mg/L.
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spelling doaj.art-deef72e4e3da4a4f9439969f2d87365e2022-12-21T21:25:44ZengElsevierAlexandria Engineering Journal1110-01682021-08-0160441154120A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detectionMeiju Luo0Qi Wang1School of Mathematics, Liaoning University, Liaoning 110036, ChinaCollege of Information Science and Engineering, Northeastern University, Shenyang 110819, China; Corresponding author.A new dissolved oxygen sensor based on optical fiber surface plasmon resonance (SPR) theory and the mechanism of oxygen transporting by hemoglobin was proposed and demonstrated. Gold film was coated on the surface of the optical fiber sensing area, and hemoglobin was modified on the surface of the gold film. The experimental results show that the sensor has good linearity and the limit of detection (LOD) of the sensor is 0.03 mg/L. In addition, in order to enhance the sensitivity of the sensor, the carbon nanotubes were modified on the surface of the gold film of the fiber, and then the hemoglobin was modified in the outermost layer. Through experiments, it was found that the sensitivity of the sensor which modified with carbon nanotubes is 2.8-folds higher than that only modified hemoglobin, the linearity is better, and the LOD is reduced to 0.01 mg/L.http://www.sciencedirect.com/science/article/pii/S1110016820306852Dissolved oxygenSurface plasmon resonanceHemoglobinCarbon nanotubesOptical fiber sensor
spellingShingle Meiju Luo
Qi Wang
A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection
Alexandria Engineering Journal
Dissolved oxygen
Surface plasmon resonance
Hemoglobin
Carbon nanotubes
Optical fiber sensor
title A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection
title_full A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection
title_fullStr A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection
title_full_unstemmed A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection
title_short A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection
title_sort reflective optical fiber spr sensor with surface modified hemoglobin for dissolved oxygen detection
topic Dissolved oxygen
Surface plasmon resonance
Hemoglobin
Carbon nanotubes
Optical fiber sensor
url http://www.sciencedirect.com/science/article/pii/S1110016820306852
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