Hairy Projections on Non Hairy Cells- A Case Report

Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2, CD3 and CD5. These leukaemic cells are high...

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Main Authors: Rhituparna Das, Sriranjan Mukherjee, Moumita Sengupta
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2021-08-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/15289/49864_CE[Ra1]_F[SK]_PF1(MG_SHU)_PFA(MG_KM)_PN(KM).pdf
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author Rhituparna Das
Sriranjan Mukherjee
Moumita Sengupta
author_facet Rhituparna Das
Sriranjan Mukherjee
Moumita Sengupta
author_sort Rhituparna Das
collection DOAJ
description Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2, CD3 and CD5. These leukaemic cells are highly pleomorphic in light microscopic appearance and also they have a highly variable clinical presentation ranging from acute to lymphomatous to chronic to smouldering. There is a chance of missed or miss diagnosis due to their morphological and clinical heterogeneity and specialised test like immunophenotyping or flow cytometry is essential for exact categorisation. Authors hereby, report a case of 45-year-old female patient suffering from ATLL whose peripheral smear showed leukaemic cells with unusual hairy projections resembling hairy cell leukaemia posing diagnostic dilemma.
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spelling doaj.art-deef9f933ef84f269af4f24d77415be02022-12-21T20:00:22ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-08-01158ED20ED2110.7860/JCDR/2021/49864.15289Hairy Projections on Non Hairy Cells- A Case ReportRhituparna Das0Sriranjan Mukherjee1Moumita Sengupta2Junior Resident, Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.Junior Resident, Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.Associate Professor, Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2, CD3 and CD5. These leukaemic cells are highly pleomorphic in light microscopic appearance and also they have a highly variable clinical presentation ranging from acute to lymphomatous to chronic to smouldering. There is a chance of missed or miss diagnosis due to their morphological and clinical heterogeneity and specialised test like immunophenotyping or flow cytometry is essential for exact categorisation. Authors hereby, report a case of 45-year-old female patient suffering from ATLL whose peripheral smear showed leukaemic cells with unusual hairy projections resembling hairy cell leukaemia posing diagnostic dilemma.https://jcdr.net/articles/PDF/15289/49864_CE[Ra1]_F[SK]_PF1(MG_SHU)_PFA(MG_KM)_PN(KM).pdfadult t-cell leukaemiahair like projectionslight microscopy
spellingShingle Rhituparna Das
Sriranjan Mukherjee
Moumita Sengupta
Hairy Projections on Non Hairy Cells- A Case Report
Journal of Clinical and Diagnostic Research
adult t-cell leukaemia
hair like projections
light microscopy
title Hairy Projections on Non Hairy Cells- A Case Report
title_full Hairy Projections on Non Hairy Cells- A Case Report
title_fullStr Hairy Projections on Non Hairy Cells- A Case Report
title_full_unstemmed Hairy Projections on Non Hairy Cells- A Case Report
title_short Hairy Projections on Non Hairy Cells- A Case Report
title_sort hairy projections on non hairy cells a case report
topic adult t-cell leukaemia
hair like projections
light microscopy
url https://jcdr.net/articles/PDF/15289/49864_CE[Ra1]_F[SK]_PF1(MG_SHU)_PFA(MG_KM)_PN(KM).pdf
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