Regulation of membrane ruffling by polarized STIM1 and ORAI1 in cortactin-rich domains
Abstract Cell motility and migration requires the reorganization of the cortical cytoskeleton at the leading edge of cells and extracellular Ca2+ entry is essential for this reorganization. However the molecular nature of the regulators of this pathway is unknown. This work contributes to understand...
Main Authors: | Aida M. Lopez-Guerrero, Patricia Tomas-Martin, Carlos Pascual-Caro, Thomas Macartney, Alejandro Rojas-Fernandez, Graeme Ball, Dario R. Alessi, Eulalia Pozo-Guisado, Francisco Javier Martin-Romero |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-00331-4 |
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