Complexities of Prostate Cancer
Prostate cancer has a long disease history and a wide variety and uncertainty in individual patients’ clinical progress. In recent years, we have seen a revolutionary advance in both prostate cancer patient care and in the research field. The power of deep sequencing has provided cistromic and trans...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/22/14257 |
| _version_ | 1797465062319849472 |
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| author | Sobia Wasim Sang-Yoon Lee Jaehong Kim |
| author_facet | Sobia Wasim Sang-Yoon Lee Jaehong Kim |
| author_sort | Sobia Wasim |
| collection | DOAJ |
| description | Prostate cancer has a long disease history and a wide variety and uncertainty in individual patients’ clinical progress. In recent years, we have seen a revolutionary advance in both prostate cancer patient care and in the research field. The power of deep sequencing has provided cistromic and transcriptomic knowledge of prostate cancer that has not discovered before. Our understanding of prostate cancer biology, from bedside and molecular imaging techniques, has also been greatly advanced. It is important that our current theragnostic schemes, including our diagnostic modalities, therapeutic responses, and the drugs available to target non-AR signaling should be improved. This review article discusses the current progress in the understanding of prostate cancer biology and the recent advances in diagnostic and therapeutic strategies. |
| first_indexed | 2024-03-09T18:17:07Z |
| format | Article |
| id | doaj.art-def54d3ed36d490c98a0e98584da0a3e |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T18:17:07Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-def54d3ed36d490c98a0e98584da0a3e2023-11-24T08:41:08ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-11-0123221425710.3390/ijms232214257Complexities of Prostate CancerSobia Wasim0Sang-Yoon Lee1Jaehong Kim2Department of Neuroscience, College of Medicine, Gachon University, Incheon 21936, Republic of KoreaDepartment of Neuroscience, College of Medicine, Gachon University, Incheon 21936, Republic of KoreaDepartment of Biochemistry, College of Medicine, Gachon University, Incheon 21999, Republic of KoreaProstate cancer has a long disease history and a wide variety and uncertainty in individual patients’ clinical progress. In recent years, we have seen a revolutionary advance in both prostate cancer patient care and in the research field. The power of deep sequencing has provided cistromic and transcriptomic knowledge of prostate cancer that has not discovered before. Our understanding of prostate cancer biology, from bedside and molecular imaging techniques, has also been greatly advanced. It is important that our current theragnostic schemes, including our diagnostic modalities, therapeutic responses, and the drugs available to target non-AR signaling should be improved. This review article discusses the current progress in the understanding of prostate cancer biology and the recent advances in diagnostic and therapeutic strategies.https://www.mdpi.com/1422-0067/23/22/14257prostate cancerPSAresistancemutationAR signaling |
| spellingShingle | Sobia Wasim Sang-Yoon Lee Jaehong Kim Complexities of Prostate Cancer International Journal of Molecular Sciences prostate cancer PSA resistance mutation AR signaling |
| title | Complexities of Prostate Cancer |
| title_full | Complexities of Prostate Cancer |
| title_fullStr | Complexities of Prostate Cancer |
| title_full_unstemmed | Complexities of Prostate Cancer |
| title_short | Complexities of Prostate Cancer |
| title_sort | complexities of prostate cancer |
| topic | prostate cancer PSA resistance mutation AR signaling |
| url | https://www.mdpi.com/1422-0067/23/22/14257 |
| work_keys_str_mv | AT sobiawasim complexitiesofprostatecancer AT sangyoonlee complexitiesofprostatecancer AT jaehongkim complexitiesofprostatecancer |