Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegia

The pathologic involvement of brainstem and midbrain nuclei and white matter tracts in various combinations may result in a spectrum of arithmetically derived syndromes. They include ‘one and a half syndrome’, ‘eight and a half syndrome’ and ‘fifteen and a half syndrome’. We report a case of ‘nine s...

Full description

Bibliographic Details
Main Authors: Jennifer Singhdev, Ajay Asranna, Sachin Sureshbabu, Gaurav Kumar Mittal, Sweta Singla, Sudhir Peter, Sobhana Chindripu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2018;volume=21;issue=4;spage=325;epage=327;aulast=Singhdev
_version_ 1819060284276342784
author Jennifer Singhdev
Ajay Asranna
Sachin Sureshbabu
Gaurav Kumar Mittal
Sweta Singla
Sudhir Peter
Sobhana Chindripu
author_facet Jennifer Singhdev
Ajay Asranna
Sachin Sureshbabu
Gaurav Kumar Mittal
Sweta Singla
Sudhir Peter
Sobhana Chindripu
author_sort Jennifer Singhdev
collection DOAJ
description The pathologic involvement of brainstem and midbrain nuclei and white matter tracts in various combinations may result in a spectrum of arithmetically derived syndromes. They include ‘one and a half syndrome’, ‘eight and a half syndrome’ and ‘fifteen and a half syndrome’. We report a case of ‘nine syndrome’, which has been reported more recently, caused by caused by acute pontine infarcts and characterised clinically by a combination of internuclear ophthalmolplegia, ipsilateral horizontal gaze palsy, lower motor neuron type of facial palsy, contralateral hemiparesis and hemianesthesia. We highlight the genesis of this combination of clinical signs , revisit the different variants of INO and review the literature on ‘Nine syndrome’.
first_indexed 2024-12-21T14:24:33Z
format Article
id doaj.art-def5cab7b07948be8652d9526a0134fb
institution Directory Open Access Journal
issn 0972-2327
1998-3549
language English
last_indexed 2024-12-21T14:24:33Z
publishDate 2018-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Annals of Indian Academy of Neurology
spelling doaj.art-def5cab7b07948be8652d9526a0134fb2022-12-21T19:00:42ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492018-01-0121432532710.4103/aian.AIAN_118_18Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegiaJennifer SinghdevAjay AsrannaSachin SureshbabuGaurav Kumar MittalSweta SinglaSudhir PeterSobhana ChindripuThe pathologic involvement of brainstem and midbrain nuclei and white matter tracts in various combinations may result in a spectrum of arithmetically derived syndromes. They include ‘one and a half syndrome’, ‘eight and a half syndrome’ and ‘fifteen and a half syndrome’. We report a case of ‘nine syndrome’, which has been reported more recently, caused by caused by acute pontine infarcts and characterised clinically by a combination of internuclear ophthalmolplegia, ipsilateral horizontal gaze palsy, lower motor neuron type of facial palsy, contralateral hemiparesis and hemianesthesia. We highlight the genesis of this combination of clinical signs , revisit the different variants of INO and review the literature on ‘Nine syndrome’.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2018;volume=21;issue=4;spage=325;epage=327;aulast=SinghdevBrainstem syndromesinternuclear ophthalmoplegianine syndromepontine vascular syndromes
spellingShingle Jennifer Singhdev
Ajay Asranna
Sachin Sureshbabu
Gaurav Kumar Mittal
Sweta Singla
Sudhir Peter
Sobhana Chindripu
Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegia
Annals of Indian Academy of Neurology
Brainstem syndromes
internuclear ophthalmoplegia
nine syndrome
pontine vascular syndromes
title Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegia
title_full Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegia
title_fullStr Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegia
title_full_unstemmed Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegia
title_short Nine syndrome: Case report and review of clinical signs in internuclear ophthalmoplegia
title_sort nine syndrome case report and review of clinical signs in internuclear ophthalmoplegia
topic Brainstem syndromes
internuclear ophthalmoplegia
nine syndrome
pontine vascular syndromes
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2018;volume=21;issue=4;spage=325;epage=327;aulast=Singhdev
work_keys_str_mv AT jennifersinghdev ninesyndromecasereportandreviewofclinicalsignsininternuclearophthalmoplegia
AT ajayasranna ninesyndromecasereportandreviewofclinicalsignsininternuclearophthalmoplegia
AT sachinsureshbabu ninesyndromecasereportandreviewofclinicalsignsininternuclearophthalmoplegia
AT gauravkumarmittal ninesyndromecasereportandreviewofclinicalsignsininternuclearophthalmoplegia
AT swetasingla ninesyndromecasereportandreviewofclinicalsignsininternuclearophthalmoplegia
AT sudhirpeter ninesyndromecasereportandreviewofclinicalsignsininternuclearophthalmoplegia
AT sobhanachindripu ninesyndromecasereportandreviewofclinicalsignsininternuclearophthalmoplegia