Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic Use

This paper aims to analyse the consumption of antibiotics in the Slovak health care system from 2011 to 2020. The data source on the consumption of antibiotics is sales data from SUKL and NCZI. The study employed the ATC/DDD Index and focused on the consumption of antibiotics in the primary care sec...

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Main Authors: Tomas Tesar, Lucia Masarykova, Lubica Lehocka, Slavka Porubcova, Monika Cicova, Martin Wawruch
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/10/1180
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author Tomas Tesar
Lucia Masarykova
Lubica Lehocka
Slavka Porubcova
Monika Cicova
Martin Wawruch
author_facet Tomas Tesar
Lucia Masarykova
Lubica Lehocka
Slavka Porubcova
Monika Cicova
Martin Wawruch
author_sort Tomas Tesar
collection DOAJ
description This paper aims to analyse the consumption of antibiotics in the Slovak health care system from 2011 to 2020. The data source on the consumption of antibiotics is sales data from SUKL and NCZI. The study employed the ATC/DDD Index and focused on the consumption of antibiotics in the primary care sector. Total antibiotic consumption decreased from 19.21 DID in 2011 to 13.16 DID in 2020. Consumption of beta-lactamase-sensitive penicillins, expressed as a percentage of the total consumption of antibiotics, decreased from 8.4% in 2011 to 4.2% in 2020. Consumption of the combination of penicillins, including beta-lactamase inhibitor, expressed as a percentage of the total consumption of antibiotics, increased from 16.2% in 2011 to 17.9% in 2020. Consumption of third- and fourth-generation cephalosporins, expressed as the percentage of the total consumption of antibiotics, increased from 2.0% in 2011 to 4.6% in 2020. Consumption of fluoroquinolones, expressed as the percentage of the total consumption of antibiotics, decreased from 10.7% in 2011 to 8.6% in 2020. Overall, antibiotic consumption significantly changed in Slovakia from 2011 to 2020. The ratio of the consumption of broad-spectrum to the consumption of narrow-spectrum penicillins, cephalosporins and macrolides decreased from 14.98 in 2011 to 13.38 in 2020.
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spelling doaj.art-defc77edbf23432ca20a0de23dc116302023-11-22T17:13:19ZengMDPI AGAntibiotics2079-63822021-09-011010118010.3390/antibiotics10101180Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic UseTomas Tesar0Lucia Masarykova1Lubica Lehocka2Slavka Porubcova3Monika Cicova4Martin Wawruch5Department of Organisation and Management in Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, 832 32 Bratislava, SlovakiaDepartment of Organisation and Management in Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, 832 32 Bratislava, SlovakiaDepartment of Organisation and Management in Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, 832 32 Bratislava, SlovakiaDepartment of Organisation and Management in Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, 832 32 Bratislava, SlovakiaDepartment of Organisation and Management in Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, 832 32 Bratislava, SlovakiaInstitute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University in Bratislava, 813 72 Bratislava, SlovakiaThis paper aims to analyse the consumption of antibiotics in the Slovak health care system from 2011 to 2020. The data source on the consumption of antibiotics is sales data from SUKL and NCZI. The study employed the ATC/DDD Index and focused on the consumption of antibiotics in the primary care sector. Total antibiotic consumption decreased from 19.21 DID in 2011 to 13.16 DID in 2020. Consumption of beta-lactamase-sensitive penicillins, expressed as a percentage of the total consumption of antibiotics, decreased from 8.4% in 2011 to 4.2% in 2020. Consumption of the combination of penicillins, including beta-lactamase inhibitor, expressed as a percentage of the total consumption of antibiotics, increased from 16.2% in 2011 to 17.9% in 2020. Consumption of third- and fourth-generation cephalosporins, expressed as the percentage of the total consumption of antibiotics, increased from 2.0% in 2011 to 4.6% in 2020. Consumption of fluoroquinolones, expressed as the percentage of the total consumption of antibiotics, decreased from 10.7% in 2011 to 8.6% in 2020. Overall, antibiotic consumption significantly changed in Slovakia from 2011 to 2020. The ratio of the consumption of broad-spectrum to the consumption of narrow-spectrum penicillins, cephalosporins and macrolides decreased from 14.98 in 2011 to 13.38 in 2020.https://www.mdpi.com/2079-6382/10/10/1180antibiotic consumption (AMC)defined daily dose (DDD)/1000 patient-daysquality indicatorsanatomical therapeutic chemical classification system (ATC)
spellingShingle Tomas Tesar
Lucia Masarykova
Lubica Lehocka
Slavka Porubcova
Monika Cicova
Martin Wawruch
Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic Use
Antibiotics
antibiotic consumption (AMC)
defined daily dose (DDD)/1000 patient-days
quality indicators
anatomical therapeutic chemical classification system (ATC)
title Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic Use
title_full Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic Use
title_fullStr Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic Use
title_full_unstemmed Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic Use
title_short Consumption of Antibacterials for Systemic Use in Slovakia: A National Study and the Quality Indicators for Outpatient Antibiotic Use
title_sort consumption of antibacterials for systemic use in slovakia a national study and the quality indicators for outpatient antibiotic use
topic antibiotic consumption (AMC)
defined daily dose (DDD)/1000 patient-days
quality indicators
anatomical therapeutic chemical classification system (ATC)
url https://www.mdpi.com/2079-6382/10/10/1180
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