Millisecond Timescale Motions Connect Amino Acid Interaction Networks in Alpha Tryptophan Synthase
Tryptophan synthase is a model system for understanding allosteric regulation within enzyme complexes. Amino acid interaction networks were previously delineated in the isolated alpha subunit (αTS) in the absence of the beta subunit (βTS). The amino acid interaction networks were different between t...
Main Authors: | Kathleen F. O'Rourke, Jennifer M. Axe, Rebecca N. D'Amico, Debashish Sahu, David D. Boehr |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-11-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fmolb.2018.00092/full |
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