Ribavirin inhibits the replication of infectious bursal disease virus predominantly through depletion of cellular guanosine pool

Ribavirin inhibits the replication of infectious bursal disease virus predominantly through depletion of cellular guanosine pool

IntroductionThe antiviral activity of different mutagens against single-stranded RNA viruses is well documented; however, their activity on the replication of double-stranded RNA viruses remains unexplored. This study aims to investigate the effect of different antivirals on the replication of a chi...

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Main Authors: Towseef Akram, Irfan Gul, Mahrukh Parveez Zia, Amreena Hassan, Amina Khatun, Riaz Ahmad Shah, Syed Mudasir Ahmad, Nazir Ahmad Ganai, Naveed Anjum Chikan, Won-Il Kim, Nadeem Shabir
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Veterinary Science
Subjects:
infectious bursal disease virus
ribavirin
dsRNA
antiviral
mutagen
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1192583/full

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