Construction and verification of a novel hypoxia-related lncRNA signature related with survival outcomes and immune microenvironment of bladder urothelial carcinoma by weighted gene co-expression network analysis

Construction and verification of a novel hypoxia-related lncRNA signature related with survival outcomes and immune microenvironment of bladder urothelial carcinoma by weighted gene co-expression network analysis

Background: Bladder urothelial carcinoma (BLCA) is a common malignant tumor with the greatest recurrence rate of any solid tumor. Hypoxia is crucial in the growth and immune escape of malignant tumors. To predict clinical outcomes and immunological microenvironment of patients with BLCA, a hypoxia-r...

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Bibliographic Details
Main Authors: Dawei Cai, Zhongbao Zhou, Guangzhu Wei, Peishan Wu, Guangqi Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
hypoxia
bladder urothelial carcinoma
lncRNA
prognostic signature
nomogram
overall survival
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.952369/full

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