Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusion
ObjectiveTo explore the association between laryngopharyngeal reflux disease (LPRD)-related symptoms and the Eustachian tube (ET) function in adult patients with otitis media with effusion (OME).Materials and methodsA total of 105 adult patients with OME were retrospectively studied. All these patie...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.1024743/full |
| _version_ | 1811328370745540608 |
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| author | Zhen Zhen Tingting Zhao Quangui Wang Junbo Zhang Zhen Zhong |
| author_facet | Zhen Zhen Tingting Zhao Quangui Wang Junbo Zhang Zhen Zhong |
| author_sort | Zhen Zhen |
| collection | DOAJ |
| description | ObjectiveTo explore the association between laryngopharyngeal reflux disease (LPRD)-related symptoms and the Eustachian tube (ET) function in adult patients with otitis media with effusion (OME).Materials and methodsA total of 105 adult patients with OME were retrospectively studied. All these patients had undergone tubomanometry (TMM) test for the affected ears before treatments. The LPRD-related symptoms were all assessed by the Reflux Symptom Index (RSI) scale.ResultsAmong the 105 included patients, the numbers of subjects with only one and both two ears affected were 65 (57.1%) and 40 (42.9%), respectively. Therefore, a total of 145 affected ears were studied. For these affected ears, a linear regression analysis that included sex, age, BMI, smoking history, drinking history, RSI value, and the condition of the contralateral ear suggested that only RSI value was significantly associated with TMM value (P < 0.001), with the correlation coefficient of −0.112. Among the 9 symptoms in RSI scale, affected ears with the following symptoms (vs. affected ears without) showed significantly lower TMM values: excess throat mucus or postnasal drip, difficulty swallowing food, liquids, or pills, and sensations of something stuck in your throat or a lump in your throat (all P < 0.05).ConclusionLPRD may disrupt ET function in adult OME patients. A higher RSI score is independently predictive for a bad ET patency in such patients and is indicative for an additional anti-reflux therapy. |
| first_indexed | 2024-04-13T15:23:48Z |
| format | Article |
| id | doaj.art-df030973a2174586804ae8bb03b6adcc |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-13T15:23:48Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-df030973a2174586804ae8bb03b6adcc2022-12-22T02:41:34ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-11-011310.3389/fneur.2022.10247431024743Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusionZhen Zhen0Tingting Zhao1Quangui Wang2Junbo Zhang3Zhen Zhong4Department of Otolaryngology, Head and Neck Surgery, Peking University First Hospital, Beijing, ChinaDepartment of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital and Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Peking University First Hospital, Beijing, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Peking University First Hospital, Beijing, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Peking University First Hospital, Beijing, ChinaObjectiveTo explore the association between laryngopharyngeal reflux disease (LPRD)-related symptoms and the Eustachian tube (ET) function in adult patients with otitis media with effusion (OME).Materials and methodsA total of 105 adult patients with OME were retrospectively studied. All these patients had undergone tubomanometry (TMM) test for the affected ears before treatments. The LPRD-related symptoms were all assessed by the Reflux Symptom Index (RSI) scale.ResultsAmong the 105 included patients, the numbers of subjects with only one and both two ears affected were 65 (57.1%) and 40 (42.9%), respectively. Therefore, a total of 145 affected ears were studied. For these affected ears, a linear regression analysis that included sex, age, BMI, smoking history, drinking history, RSI value, and the condition of the contralateral ear suggested that only RSI value was significantly associated with TMM value (P < 0.001), with the correlation coefficient of −0.112. Among the 9 symptoms in RSI scale, affected ears with the following symptoms (vs. affected ears without) showed significantly lower TMM values: excess throat mucus or postnasal drip, difficulty swallowing food, liquids, or pills, and sensations of something stuck in your throat or a lump in your throat (all P < 0.05).ConclusionLPRD may disrupt ET function in adult OME patients. A higher RSI score is independently predictive for a bad ET patency in such patients and is indicative for an additional anti-reflux therapy.https://www.frontiersin.org/articles/10.3389/fneur.2022.1024743/fulllaryngopharyngeal refluxEustachian tubeotitis media with effusiontubomanometry (TMM)Reflux Symptom Index (RSI) |
| spellingShingle | Zhen Zhen Tingting Zhao Quangui Wang Junbo Zhang Zhen Zhong Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusion Frontiers in Neurology laryngopharyngeal reflux Eustachian tube otitis media with effusion tubomanometry (TMM) Reflux Symptom Index (RSI) |
| title | Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusion |
| title_full | Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusion |
| title_fullStr | Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusion |
| title_full_unstemmed | Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusion |
| title_short | Laryngopharyngeal reflux as a potential cause of Eustachian tube dysfunction in patients with otitis media with effusion |
| title_sort | laryngopharyngeal reflux as a potential cause of eustachian tube dysfunction in patients with otitis media with effusion |
| topic | laryngopharyngeal reflux Eustachian tube otitis media with effusion tubomanometry (TMM) Reflux Symptom Index (RSI) |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.1024743/full |
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