Application Progress of Metal-organic Frameworks in Tumors Therapy

Metal-organic frameworks (MOFs) are special materials formed by self-assembly of metal ions and organic ligands, with special physical and chemical properties, such as large specific surface area, excellent biocompatibility and strong pH sensitivity, etc. Through modification, they have synthesized...

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Main Authors: GUO Yang, WU Suqing, WEN Zhaohui
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2022-05-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1158
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author GUO Yang
WU Suqing
WEN Zhaohui
author_facet GUO Yang
WU Suqing
WEN Zhaohui
author_sort GUO Yang
collection DOAJ
description Metal-organic frameworks (MOFs) are special materials formed by self-assembly of metal ions and organic ligands, with special physical and chemical properties, such as large specific surface area, excellent biocompatibility and strong pH sensitivity, etc. Through modification, they have synthesized nanomaterials with excellent performance, which have huge application prospects in treating tumors. This paper mainly reviews the properties of MOFs and their derived materials, and the application progress of MOFs in tumor drug-loaded therapy, photodynamic therapy and immunotherapy.
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spelling doaj.art-df038d4129ff40de8c1434a91817dba42022-12-22T02:23:06ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782022-05-0149547247710.3971/j.issn.1000-8578.2022.21.11588578.2022.21.1158Application Progress of Metal-organic Frameworks in Tumors TherapyGUO Yang0WU Suqing1WEN Zhaohui2Department of Neurology and Brain Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaDepartment of Ultrasound, Heze Municipal Hospital, Heze 274031, ChinaDepartment of Neurology and Brain Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaMetal-organic frameworks (MOFs) are special materials formed by self-assembly of metal ions and organic ligands, with special physical and chemical properties, such as large specific surface area, excellent biocompatibility and strong pH sensitivity, etc. Through modification, they have synthesized nanomaterials with excellent performance, which have huge application prospects in treating tumors. This paper mainly reviews the properties of MOFs and their derived materials, and the application progress of MOFs in tumor drug-loaded therapy, photodynamic therapy and immunotherapy.http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1158metal-organic frameworkstumorphotodynamic therapyimmunotherapy
spellingShingle GUO Yang
WU Suqing
WEN Zhaohui
Application Progress of Metal-organic Frameworks in Tumors Therapy
Zhongliu Fangzhi Yanjiu
metal-organic frameworks
tumor
photodynamic therapy
immunotherapy
title Application Progress of Metal-organic Frameworks in Tumors Therapy
title_full Application Progress of Metal-organic Frameworks in Tumors Therapy
title_fullStr Application Progress of Metal-organic Frameworks in Tumors Therapy
title_full_unstemmed Application Progress of Metal-organic Frameworks in Tumors Therapy
title_short Application Progress of Metal-organic Frameworks in Tumors Therapy
title_sort application progress of metal organic frameworks in tumors therapy
topic metal-organic frameworks
tumor
photodynamic therapy
immunotherapy
url http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1158
work_keys_str_mv AT guoyang applicationprogressofmetalorganicframeworksintumorstherapy
AT wusuqing applicationprogressofmetalorganicframeworksintumorstherapy
AT wenzhaohui applicationprogressofmetalorganicframeworksintumorstherapy