Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review
(1) Background: Antibiotics are used in every medical field including dentistry, where they are used for the prevention of postoperative complications in routine clinical practice during the third molar extraction. (2) Methods: This study is reported in accordance with the Preferred Reporting Items...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Dentistry Journal |
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| Online Access: | https://www.mdpi.com/2304-6767/10/4/72 |
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| author | Diana Sologova Ekaterina Diachkova Ilana Gor Susanna Sologova Ekaterina Grigorevskikh Liana Arazashvili Pavel Petruk Svetlana Tarasenko |
| author_facet | Diana Sologova Ekaterina Diachkova Ilana Gor Susanna Sologova Ekaterina Grigorevskikh Liana Arazashvili Pavel Petruk Svetlana Tarasenko |
| author_sort | Diana Sologova |
| collection | DOAJ |
| description | (1) Background: Antibiotics are used in every medical field including dentistry, where they are used for the prevention of postoperative complications in routine clinical practice during the third molar extraction. (2) Methods: This study is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The present systematic review aimed to evaluate and systematize the use of antibacterial drugs in order to prevent postoperative complications in outpatient oral surgery for wisdom teeth extraction. We conducted a systematic review using electronic databases such as Medline PubMed, Scopus, and the Cochrane Central Register of Controlled Trials. Considering inclusion and exclusion criteria, we included randomized clinical trials published up to 2021 investigating the antibiotic prescription for third molar extraction. (3) Results: We selected 10 studies after the application of inclusion and exclusion criteria. The results showed that the most widely used antibiotic was amoxicillin both with and without clavulanic acid, in different dosages and duration. There were no statistically significant differences between treatment groups for development of postoperative complications. (4) Conclusions: Based on the analysis of the included studies, penicillin is currently the most widely prescribed group of antibiotics. The widespread use of this antibiotic group can lead to antimicrobial resistance (AMR). Due to increasing prevalence of bacteria resistance to penicillins, clinicians should carefully prescribe these antibiotics and be aware that the widespread use of amoxicillin may do more harm than good for the population. |
| first_indexed | 2024-03-09T10:58:39Z |
| format | Article |
| id | doaj.art-df07eca4c4dd4041bd09d34d52eedefc |
| institution | Directory Open Access Journal |
| issn | 2304-6767 |
| language | English |
| last_indexed | 2024-03-09T10:58:39Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dentistry Journal |
| spelling | doaj.art-df07eca4c4dd4041bd09d34d52eedefc2023-12-01T01:30:35ZengMDPI AGDentistry Journal2304-67672022-04-011047210.3390/dj10040072Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic ReviewDiana Sologova0Ekaterina Diachkova1Ilana Gor2Susanna Sologova3Ekaterina Grigorevskikh4Liana Arazashvili5Pavel Petruk6Svetlana Tarasenko7Department of Oral Surgery of the Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119048 Moscow, RussiaDepartment of Oral Surgery of the Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119048 Moscow, RussiaDepartment of Oral Surgery of the Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119048 Moscow, RussiaDepartment of Pharmacology, Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, RussiaDepartment of Pharmacology, Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, RussiaMaxillofacial Surgery Department, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya Str., 119991 Moscow, RussiaMaxillofacial Surgery Department, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya Str., 119991 Moscow, RussiaDepartment of Oral Surgery of the Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119048 Moscow, Russia(1) Background: Antibiotics are used in every medical field including dentistry, where they are used for the prevention of postoperative complications in routine clinical practice during the third molar extraction. (2) Methods: This study is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The present systematic review aimed to evaluate and systematize the use of antibacterial drugs in order to prevent postoperative complications in outpatient oral surgery for wisdom teeth extraction. We conducted a systematic review using electronic databases such as Medline PubMed, Scopus, and the Cochrane Central Register of Controlled Trials. Considering inclusion and exclusion criteria, we included randomized clinical trials published up to 2021 investigating the antibiotic prescription for third molar extraction. (3) Results: We selected 10 studies after the application of inclusion and exclusion criteria. The results showed that the most widely used antibiotic was amoxicillin both with and without clavulanic acid, in different dosages and duration. There were no statistically significant differences between treatment groups for development of postoperative complications. (4) Conclusions: Based on the analysis of the included studies, penicillin is currently the most widely prescribed group of antibiotics. The widespread use of this antibiotic group can lead to antimicrobial resistance (AMR). Due to increasing prevalence of bacteria resistance to penicillins, clinicians should carefully prescribe these antibiotics and be aware that the widespread use of amoxicillin may do more harm than good for the population.https://www.mdpi.com/2304-6767/10/4/72third molarextractionantibioticprophylaxissystematic review |
| spellingShingle | Diana Sologova Ekaterina Diachkova Ilana Gor Susanna Sologova Ekaterina Grigorevskikh Liana Arazashvili Pavel Petruk Svetlana Tarasenko Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review Dentistry Journal third molar extraction antibiotic prophylaxis systematic review |
| title | Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review |
| title_full | Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review |
| title_fullStr | Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review |
| title_full_unstemmed | Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review |
| title_short | Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review |
| title_sort | antibiotics efficiency in the infection complications prevention after third molar extraction a systematic review |
| topic | third molar extraction antibiotic prophylaxis systematic review |
| url | https://www.mdpi.com/2304-6767/10/4/72 |
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